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Overview

This sixth edition of the Oxford Textbook of Palliative Medicine takes us now into the third decade for this definitive award-winning textbook. It has been rigorously updated to offer a truly global perspective, highlighting the best current evidence-based practices, and collective wisdom from more than 200 experts around the world.

This leading textbook covers all the new and emerging topics, updated and restructured to reflect major developments in the increasingly widespread acceptance of palliative medicine as a fundamental public health need. The sixth edition includes new sections devoted to family and caregiver issues, cardio-respiratory symptoms and disorders, and genitourinary symptoms and disorders. In addition, the multi-disciplinary nature of palliative care is emphasized throughout the textbook, covering areas from ethical and communication issues, the treatment of symptoms, and the management of pain.

The Oxford Textbook of Palliative Medicine is a truly comprehensive text. No hospital, hospice, palliative care service, or medical library should be without this essential source of information.

This sixth edition of the Oxford Textbook of Palliative Medicine is dedicated to the memory of Professor Kenneth Fearon husband of Professor Marie Fallon and a surgeon who became a world leader in the research and management of anorexia and cachexia. He modeled a work-life balance that is so critical in our field, with devotion to both his patients and his family.

Product Details

ISBN-13: 9780198900597
Publisher: Oxford University Press
Publication date: 05/02/2024
Series: Oxford Textbook
Edition description: 6th ed.
Pages: 1408
Sales rank: 1,020,592
Product dimensions: 10.80(w) x 8.40(h) x 2.10(d)

About the Author

Nathan I. Cherny, Norman Levan Chair of Humanistic Medicine, Chief Cancer Pain and Palliative Medicine Service, Department of Oncology, Shaare Zedek Medical Center, Jerusalem, Israel,Marie T. Fallon, St Columba's Hospice Chair of Palliative Medicine, University of Edinburgh, UK,Stein Kaasa, Oslo University Hospital, Department of Oncology; and University of Oslo, Institute of Clinical Medicine, Oslo, Norway,Russell K. Portenoy, Executive Director and Chief Medical Officer of the MJHS Institute for Innovation in Palliative Care and is Professor of Neurology and Family and Social Medicine at the Albert Einstein College of Medicine, New York,David C. Currow, Professor of Palliative Medicine at University of Technology Sydney, the Matthew Flinders Distinguished Professor of Palliative and Supportive Care, Flinders University and Associate Director (Research) at the Wolfson Palliative Care Research Centre, University of Hull, UK.

Nathan I. Cherny is Norman Levan Chair of Humanistic Medicine at Shaare Zedek Medical Center and Associate Professor of Medicine at Ben Gurion University, Israel. In 2015 he was awarded the ESMO (European Society of Medical Oncology) Award for his contributions to the development of oncology in Europe, and in 2016 was the recipient of the EAPC/EJPC (European Association of Palliative Care/ European Journal of Palliative Care) Palliative Care Policy Development Award. Nathan has diverse research interests including opioid responsiveness of neuropathic pain, opioid rotation, opioid side effects and their management, cancer pain syndromes, suffering, palliative sedation, communication issues in oncology and palliative care, bioethics, and public health. He teaches in the Hebrew University Medical School and runs courses in communication and palliative medicine. Nathan has edited five books and has published over 120 peer reviewed papers and has made numerous invited lectures worldwide.


Marie T. Fallon is the St Columba's Hospice Chair of Palliative Medicine at the University of Edinburgh, Honorary Consultant in Palliative Care at the Western General Hospital in Edinburgh and leads the Edinburgh Palliative and Supportive Care group (EpaS). Marie serves as Chief Investigator for EpaS on a large portfolio of clinical studies spanning investigator-led randomized controlled trials examining improved management of cancer-induced bone pain, neuropathic pain, and institutionalisation of pain assessment. Marie is also the lead in an international programme of RCTs in cannabinoids in cancer-related pain and has led the development of studies using fMRI in Edinburgh, UK.


Stein Kaasa is Professor of Palliative Medicine at the Institute of Cancer Research and Molecular Medicine at the Norwegian University of Science and Technology (NTNU), Norway. Stein specialises in medical oncology, radiotherapy, and palliative medicine. In 1993, he was appointed as the first professor in palliative medicine in Scandinavia and he was one of the founders of the palliative care unit in Trondheim and founder of the European Palliative Care Research Centre (PRC). He has been president of EAPC, the coordinator for a large EU-funded project, and is at present involved in several research collaborative and international partnerships on research and policy development. Stein has been an important advocate for evidence-based practice and has worked extensively to get palliative care research on the global agenda. Stein is also Director of the PRC and Chair of the European Association for Palliative Care Research Network and has published more than 450 articles and book chapters.


Russell K. Portenoy is Executive Director and Chief Medical Officer of the MJHS Institute for Innovation in Palliative Care and is Professor of Neurology and Family and Social Medicine at the Albert Einstein College of Medicine, New York. Prior to joining MJHS, he was founding Chairman of the Department of Pain Medicine and Palliative Care and the Gerald J. Friedman Chair in Pain Medicine and Palliative Care at Mount Sinai Beth Israel Medical Center. Russell is Past President of both the American Academy of Hospice and Palliative Medicine and the American Pain Society. He previously chaired the American Board of Hospice and Palliative Medicine. Russell is recipient of the Lifetime Achievement Award, the National Leadership Award of the American Academy of Hospice and Palliative Medicine, the Wilbert Fordyce Award for Lifetime Excellence in Clinical Investigation, the Distinguished Service Award from the American Pain Society, and the Founder's Award by the American Academy of Pain Medicine.


David C. Currow is Professor of Palliative Medicine at University of Technology Sydney, the Matthew Flinders Distinguished Professor of Palliative and Supportive Care, Flinders University and Associate Director (Research) at the Wolfson Palliative Care Research Centre, University of Hull, UK. Research includes clinical trials and use of large datasets to understand better the impact of life-limiting illnesses on patients and caregivers. Research into chronic breathlessness is a particular area of interest. He is the principal investigator for the Australian national Palliative Care Clinical Studies Collaborative (PaCCSC) and is a foundation partner in the Australian national Palliative Care Outcomes Collaborative (PCOC), an initiative to improve palliative care clinical outcomes through point-of-care data collection.

Table of Contents

Section 1: The worldwide status of palliative care1.1. International progress in the development of palliative care, Carlos Centeno, Sheila Payne, and Eduardo Garralda1.2. Essential medicines for palliative care, Lukas Radbruch and Liliana De Lima1.3. Human rights issues, Frank Brennan and Liz Gwyther1.4. Policy in palliative care, Stephen R. ConnorSection 2: The challenge of palliative medicine2.1. Building definitional consensus in palliative care, Russell K. Portenoy2.2. Core concepts in palliative care, Nathan I. Cherny and Russell K. Portenoy2.3. The epidemiology of death and symptoms: planning for population-based palliative care, Davinia Seah, David Marco, Jennifer Philip, and Megan B. Sands2.4. Barriers to the delivery of palliative care, Barry Laird, Erna Haraldsdottir, and Charlie Hall2.5. Ethnic and cultural aspects of palliative and end of life care, Jonathan Koffman and Natalia Calanzani2.6. Health economics for palliative care, Peter S. Hall, Katharina Diernberger, and Liz GrantSection 3: Service delivery issues in palliative care3.1. Specialist palliative care along the trajectory of illness: issues in the early integration of palliative care, Breffni Hannon, Stein Kaasa, and Camilla Zimmermann3.2. Palliative care delivery models, Irene J. Higginson3.3. Palliative medicine in the intensive care unit, Sharon Einav, Nathan I. Cherny, and J. Randall Curtis3.4. Palliative care in the emergency department, Naomi George and Corita Grudzen3.5. Palliative care in the nursing home, Jane Phillips and Annmarie HosieSection 4: Healthcare professionals in palliative care4.1. The core team and the extended team, Dagny Faksvåg Haugen, Friedemann Nauck, and Deborah Witt Sherman4.2. Burnout, compassion fatigue, and moral distress in palliative care, Nathan I. Cherny, Batsheva Werman, and Michael Kearney4.3. Nursing Education in palliative care, Betty R. Ferrell, Polly Mazanec, Pam Malloy, and Rose Virani4.4. Social work in palliative care, Terry Altilio, Bridget Sumser, and Nina Laing4.5. The role of the chaplain in palliative care, George Handzo and Christina Puchalski4.6. Occupational therapy in palliative care, Maria Denise Pessoa Silva, Fiona Rolls, Lynne White, Tamsin Longley, Jane Murphy, and Jill Cooper4.7. The role of the creative arts in palliative care, Nigel Hartley4.8. The role of the dietitian in palliative care, Samantha Cushen and Aoife Ryan4.9. Physiotherapy in palliative care, Lucy Fettes and Matthew Maddocks4.10. Speech and language therapy in palliative care, Tim Luckett and Katherine L.P. Reid4.11. Clinical psychology in palliative care, E. Alessandra Strada4.12. The contribution of the clinical pharmacist in palliative care, Ebtesam Ahmed4.13. Medical rehabilitation and the palliative care patient, Andrew M. ColeSection 5: Communication and palliative medicine5.1. Communication with the patient and family, Thomas W. LeBlanc and James Tulsky5.2. Practical considerations including difficult conversations, Susan D. Block5.3. Advance care planning, Judith Rietjens, Ida Korfage, and Jane SeymourSection 6: Family and caregiver issues6.1. Family dynamics in the context of serious illness, Carrie Lethborg and David W. Kissane6.2. Caregiver burden and distress, Rinat Nissim, Sarah Hales, and Gary RodinSection 7: Pain7.1. Definition and assessment of chronic pain in advanced disease, Lucy N. Wyld, Clare Rayment, and Mike I. Bennett7.2. Pathophysiology of pain in cancer and other terminal illnesses, Anthony H. Dickenson and Richard Gordon-Williams7.3. Acute cancer pain syndromes, Nathan I. Cherny7.4. Chronic cancer pain syndromes, Nathan I. Cherny7.5. Principles of drug therapy, Ruth Miles, Steven Wanklyn, and Joy Ross7.6. Opioid therapy: optimizing analgesic outcomes, Nathan I. Cherny and Marie T. Fallon7.7. Opioid therapy: managing risks of abuse, addiction, and diversion, Joseph V. Pergolizzi, Jr., Jo Ann LeQuang, Flaminia Coluzzi, Dean Mariano, Andrew Nicolaou, and Christopher Gharibo7.8. Non-opioid analgesics, Per Sjøgren, Frank Elsner, and Stein Kaasa7.9. Adjuvant analgesics: principles of use, Russell K. Portenoy, Ebtesam Ahmed, and Mona Patel7.10. Interventional approaches for chronic pain, Robert A. Swarm, Menelaos Karanikolas, Lesley K. Rao, and Rajiv K. Shah7.11. Neurostimulation in pain management, Helena Knotkova7.12. Behavioral and psychosocial interventions for pain management, Joseph Winger, Carolyn E. Keeler, and Francis Keefe7.13. Integrative medicine therapies in pain management, Noah Samuels and Eran Ben-Arye7.14. Management issues in bone pain, Peter Hoskin7.15. Management issues in neuropathic pain, Lise Ventzel and Nanna Finnerup7.16. Management issues in visceral pain, Victor T. Chang7.17. Management issues in chronic pain following cancer therapy, Judith A. Paice7.18. Paediatric pain control, Renee McCullochSection 8: Gastrointestinal symptoms and disorders8.1. Dysphagia, dyspepsia, and hiccups, Katherine Clark8.2. Nausea and vomiting, Saskie Dorman8.3. Constipation and diarrhoea, Philip J. Larkin8.4. Jaundice, ascites, and encephalopathy, Alexandra Shingina and Anne M. Larson8.5. Aetiology, classification, assessment, and treatment of the anorexia-cachexia syndrome, Vickie Baracos and Sharon M. Watanabe8.6. Parenteral nutrition, Jann Arends and Florian StrasserSection 9: Cardio-respiratory symptoms and disorders9.1. Breathlessness and other respiratory symptoms in palliative care, Miriam J. Johnson and David C. Currow9.2. Cough and other pulmonary symptoms, Doris Tse and Kin-Sang ChanSection 10: Skin and oral symptoms and disorders10.1. Skin problems in palliative care, Sebastian Probst and Georgina Gethin10.2. Palliative wound and ostomy care, Charles P. Tilley, Mei R. Fu, Janet H. Van Cleave, Allison R. Most, and Christopher Comfort10.3. Lymphoedema and oedema of advanced disease, Vaughan Keeley10.4. Oral care, Andrew N. DaviesSection 11: Genitourinary symptoms and disorders11.1. Dysuria, frequency, and bladder spasm, Jennifer G. Rothschild, Noah E. Canvasser, Frederick J. Meyers, and Christopher Evans,11.2. Obstructive urinary disorders, Noah E. Canvasser, Jennifer G. Rothschild, Frederick J. Meyers, and Christopher P. EvansSection 12: Constitutional symptoms and related disorders12.1. Fatigue, Sriram Yennurajalingam and Eduardo Bruera12.2. Sexuality in palliative care: discussing patient sexuality and intimacy in palliative care, Lauren Kadwell, Jane Ussher, Emilee Gilbert, Janette Perz, and Amanda Hordern12.3. Sleep disorders, Kyriaki Mystakidou, Efi Parpa, and Eleni Tsilika12.4. Assessment and management of thrombotic complications, Simon Noble, Nicola Pease, and Nicholas Chinn-Yee12.5. Assessment and management of bleeding complications in the medically ill, Bill Hulme, Sarah Wilcox, Paul Ashwood, Laura Deacon, Hazel Gilkes, and Victoria MontgomerySection 13: Psychiatric and psychological symptoms and disorders13.1. Coping and resilience in palliative medicine, Tzeela Cohen and Simon Wein13.2. Depression, demoralization, and suicidality, David W. Kissane13.3. Fear, anxiety, and adjustment disorder in palliative care, Kerry A. Sherman and Christopher J. Kilby13.4. Delirium, Meera Agar, Yesne Alici, Augusto Caraceni, and William Breitbart13.5. Bereavement, David W. KissaneSection 14: Palliative care in cancer14.1. The oncologist s role in delivering palliative care, Nathan I. Cherny and Stein Kaasa14.2. Disease-modifying therapies in advanced cancer-medical treatment, Olav Dajani and Karin Jordan14.3. Radiotherapy in symptom management, Peter Hoskin14.4. The role of general surgery in the palliative care of patients with cancer, Robert Krouse and Brian Badgwell14.5. Orthopaedic surgery in the palliation of cancer, Mohamed Yakoub and John Healey14.6. Integrative oncology in palliative medicine, Eran Ben-Arye and Noah Samuels14.7. Interventional radiology in the palliation of cancer, Tarun Sabharwal, Nicos I. Fotiadis, and Andy Adam14.8. Neurological problems in advanced cancer, Augusto Caraceni, Fabio Simonetti, and Cinzia Martini14.9. Endocrine and metabolic complications of advanced cancer, Richella Ryan and Ruth Casey14.10. Malignant Bowel obstruction, Jason W. Boland and Elaine G. Boland14.11. Palliative care issues in head and neck cancers, Catriona R. Mayland and Simon N. Rogers14.12. Palliative care issues in populations with haematological malignancies, Thomas W. LeBlanc and Arjee El-Jawahri14.13. Anaemia, cytopenias, and thrombosis in palliative medicine, Nancy Zhu and Cynthia WuSection 15: Issues in populations with non-cancer illnesses15.1. HIV/AIDS, Meera Pahuja and Peter Selwyn15.2. Advanced diseases of the lung, Natasha Smallwood and Nicole Goh15.3. Advanced heart disease, Steve Pantilat, Patricia Davidson, and Mitch Psotka15.4. Dementia, Eric Widera, Shaida Talebreza, and Rachelle E. Bernacki15.5. Neurological disorders other than dementia, Stefan Lorenzl and Raymond Voltz15.6. Palliative care and end-stage liver disease, Arpan Patel and Anne Walling15.7. End-stage kidney disease, Fliss E.M. Murtagh15.8. Palliative care in catastrophic disasters and humanitarian crises, Anne Wilkinson and Marianne MatzoSection 16: Issues of the very young and the very old16.1. Involving children and families when someone important is dying or has died, Erna Haraldsdottir and Sally Paul16.2. Care of children with advanced illness, Myra Bluebond-Langner, Richard W. Langner, and Ignasi Clemente16.3. Palliative medicine and care of the elderly, Meera Agar and Jane PhillipsSection 17: Spiritual issues in palliative medicine17.1. Spiritual issues in palliative medicine, Susan McClement, Genevieve Thompson, and Jamie Penner17.2. Integration of spiritual care into palliative care service delivery models, Yvan Beaussant, Alexandra Nichipor, and Tracy A. BalboniSection 18: The terminal phase18.1. Predicting survival in patients with advanced disease, Christian T. Sinclair18.2. Physiology of dying, David Hui and Masanori Mori18.3. Management of the actively dying patient, Judith Lacey and Nathan I. ChernySection 19: Ethical issues19.1. Practical bioethics in the care of patients with advanced illness, Robert C. Macauley19.2. Requests for futile or inappropriate interventions near the end of life, Alexander A. Kon19.3. Autonomy and shared decision making in a multi-cultural world, Nathan I. Cherny19.4. Truth-telling and consent, Linda Emanuel, Rebecca Johnson, and Lara Boyken19.5. Ethics in paediatric palliative care, Richard D.W. Hain19.6. Ethical issues in physician aid-in-dying, Lars Johan Materstvedt19.7. Withholding and withdrawing life-sustaining treatment (including artificial nutrition and hydration), Danielle Ko, Hannah Evans-Barns, and Craig Blinderman19.8. Medical and ethical considerations in palliative sedation at the end of life, Eric L. KrakauerSection 20: Assessment tools and Informatics20.1. Palliative care needs assessment tools, Afaf Girgis, Amy Waller, and Breanne Hobden20.2. Informatics and literature search, Jennifer Tieman and David C. Currow20.3. Validated assessment tools for psychological, spiritual, and family issues, Madeline Li, Tracy A. Balboni, Rinat Nissim, and Gary RodinSection 21: Teaching and training in palliative medicine21.1. Physicians, Karen Forbes and Jane Gibbins21.2. Nurses, Geana Paula Kurita and Philip J. Larkin21.3. Teaching and training in palliative social work, chaplaincy, and pharmacy, Myra Glajchen, George Handzo, and Ebtesam AhmedSection 22: Research in palliative medicine22.1. Research in palliative care, Marianne J. Hjermstad and Stein Kaasa22.2. The principles of evidence-based medicine, Miriam J. Johnson and David C. Currow22.3. Understanding clinical trials in palliative care research, Pål Klepstad and Stein Kaasa22.4. Qualitative research, Kate Flemming22.5. Research into psychosocial issues, David K. Kissane, Christopher H. Grossman, and Clare O'Callaghan22.6. Ethical issues in palliative care research, Tyler Tate and David Casarett22.7. Quality of life and patient-reported outcome measures, Jon Håvard Loge and Stein Kaasa22.8. Health services research in palliative and end-of-life care, Tinne Smets and Luc Deliens22.9. Clinical audit in palliative medicine, Irene J. Higginson and Mevhibe B. Hocaoglu
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