Oxygen: Creating a New Paradigm
This unique work from acclaimed author Dr. Paul Marino (Marino’s The ICU Book, The Little ICU Book) challenges the traditional notion that the human body thrives on oxygen, and that promoting tissue oxygenation is necessary for promoting life. This concept fails to recognize that oxygen is a destructive molecule that also damages the human body.  Instead of welcoming oxygen, the human body limits exposure of the tissues to oxygen, and employs an army of chemical antioxidants to combat the damaging effects of oxygen.  This “oxygen protective” human design represents a new paradigm for the relationship between oxygen and human survival, and it has important implications for the excessive and unregulated use of oxygen in clinical practice. Dr. Marino’s book includes the following  relevant features:
  • Describes how oxygen and its reactive derivatives can damage vital cell components, and how oxygen plays a pivotal role in the damaging effects of inflammation, radiation, and aging.
  • Challenges the traditional notion that oxygen delivery is the principal function of the cardiorespiratory system, and that oxygen transport is the principal function of red blood cells and hemoglobin.
  • Demonstrates how the tissues normally operate in an oxygen-poor environment (which limits the risk of oxidative damage), and how the body counteracts attempts to increase tissue oxygenation.
  • Describes the body’s use of protective antioxidants, and shows how failure to maintain this antioxidant protection makes oxygen inhalation an unrecognized source of harm.
  • Reveals the lack of evidence that cellular hypoxia is a final common pathway for cell death, and proposes that oxygen itself is responsible for the death of aerobic organisms.
  • Proposes a new management strategy that is “oxygen-protective” rather than “oxygen-promoting.”
Enrich Your eBook Reading Experience
  • Read directly on your preferred device(s), such as computer, tablet, or smartphone.
  • Easily convert to audiobook, powering your content with natural language text-to-speech.
1139822981
Oxygen: Creating a New Paradigm
This unique work from acclaimed author Dr. Paul Marino (Marino’s The ICU Book, The Little ICU Book) challenges the traditional notion that the human body thrives on oxygen, and that promoting tissue oxygenation is necessary for promoting life. This concept fails to recognize that oxygen is a destructive molecule that also damages the human body.  Instead of welcoming oxygen, the human body limits exposure of the tissues to oxygen, and employs an army of chemical antioxidants to combat the damaging effects of oxygen.  This “oxygen protective” human design represents a new paradigm for the relationship between oxygen and human survival, and it has important implications for the excessive and unregulated use of oxygen in clinical practice. Dr. Marino’s book includes the following  relevant features:
  • Describes how oxygen and its reactive derivatives can damage vital cell components, and how oxygen plays a pivotal role in the damaging effects of inflammation, radiation, and aging.
  • Challenges the traditional notion that oxygen delivery is the principal function of the cardiorespiratory system, and that oxygen transport is the principal function of red blood cells and hemoglobin.
  • Demonstrates how the tissues normally operate in an oxygen-poor environment (which limits the risk of oxidative damage), and how the body counteracts attempts to increase tissue oxygenation.
  • Describes the body’s use of protective antioxidants, and shows how failure to maintain this antioxidant protection makes oxygen inhalation an unrecognized source of harm.
  • Reveals the lack of evidence that cellular hypoxia is a final common pathway for cell death, and proposes that oxygen itself is responsible for the death of aerobic organisms.
  • Proposes a new management strategy that is “oxygen-protective” rather than “oxygen-promoting.”
Enrich Your eBook Reading Experience
  • Read directly on your preferred device(s), such as computer, tablet, or smartphone.
  • Easily convert to audiobook, powering your content with natural language text-to-speech.
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Oxygen: Creating a New Paradigm

Oxygen: Creating a New Paradigm

by Paul L Marino MD, PhD
Oxygen: Creating a New Paradigm

Oxygen: Creating a New Paradigm

by Paul L Marino MD, PhD

Paperback(First)

$57.99 
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Overview

This unique work from acclaimed author Dr. Paul Marino (Marino’s The ICU Book, The Little ICU Book) challenges the traditional notion that the human body thrives on oxygen, and that promoting tissue oxygenation is necessary for promoting life. This concept fails to recognize that oxygen is a destructive molecule that also damages the human body.  Instead of welcoming oxygen, the human body limits exposure of the tissues to oxygen, and employs an army of chemical antioxidants to combat the damaging effects of oxygen.  This “oxygen protective” human design represents a new paradigm for the relationship between oxygen and human survival, and it has important implications for the excessive and unregulated use of oxygen in clinical practice. Dr. Marino’s book includes the following  relevant features:
  • Describes how oxygen and its reactive derivatives can damage vital cell components, and how oxygen plays a pivotal role in the damaging effects of inflammation, radiation, and aging.
  • Challenges the traditional notion that oxygen delivery is the principal function of the cardiorespiratory system, and that oxygen transport is the principal function of red blood cells and hemoglobin.
  • Demonstrates how the tissues normally operate in an oxygen-poor environment (which limits the risk of oxidative damage), and how the body counteracts attempts to increase tissue oxygenation.
  • Describes the body’s use of protective antioxidants, and shows how failure to maintain this antioxidant protection makes oxygen inhalation an unrecognized source of harm.
  • Reveals the lack of evidence that cellular hypoxia is a final common pathway for cell death, and proposes that oxygen itself is responsible for the death of aerobic organisms.
  • Proposes a new management strategy that is “oxygen-protective” rather than “oxygen-promoting.”
Enrich Your eBook Reading Experience
  • Read directly on your preferred device(s), such as computer, tablet, or smartphone.
  • Easily convert to audiobook, powering your content with natural language text-to-speech.

Product Details

ISBN-13: 9781496394842
Publisher: LWW
Publication date: 11/05/2021
Edition description: First
Pages: 234
Product dimensions: 5.00(w) x 8.00(h) x (d)

Table of Contents

Section I How Important Is Oxygen?

1 Is O2 delivery the principal function of the cardiorespiratory system? 3

2 Is O2 transport the principal function of hemoglobin? 15

3 How much oxygen is in tissues? 27

4 Is tissue hypoxia a common cause of death? 39

5 Is oxygen therapy based on tissue needs? 55

6 Are red blood cell transfusions based on tissue needs? 71

Section II How Destructive Is Oxygen?

7 What is oxidation? 87

8 What are reactive oxygen species? 103

9 Does oxygen participate in the inflammatory response? 123

10 What does oxygen have in common with ionizing radiation? 137

11 Does oxygen promote aging? 149

12 Why do our bodies decompose after we die? 161

13 When is oxygen therapy safe? 181

Section III What Now?

14 What is the new oxygen paradigm? 197

Appendix: Other books of Interest 207

Index 209

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