Protein Supersecondary Structures

by Alexander E. Kister (Editor)

Overview

Super secondary structure(SSS) helps to understand the relationship between primary and tertiary structure of proteins. In Protein Supersecondary Structure: Methods and Prools expert researchers in the field detail the usefulness of the study of super secondary structure in different areas of protein research. This is done through four main studies SSS representation, SSS prediction, SSS and protein folding, and other application of SSS concept to protein biology. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory prools, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Protein Supersecondary Structure: Methods and Prools highlight some of the major advances in the many fast-growing areas of supersecondary structure research.

Product Details

ISBN-13:	9781493962495
Publisher:	Springer-Verlag New York, LLC
Publication date:	08/23/2016
Series:	Methods in Molecular Biology , #932
Edition description:	Softcover reprint of the original 1st ed. 2013
Pages:	320
Product dimensions:	7.01(w) x 10.00(h) x 0.03(d)

Table of Contents

Super-secondary Structure: A Historical Perspective.-Hierarchical Representation of Super-secondary Structures Using a Graph-theoretical Approach.-Up, Down and Around: Identifying Recurrent Interactions Within and Between Super Secondary Structures in b-Propellers.-Structure Description and Identification using the Tableau Representation of Protein Folding Patterns.-Computational Prediction of Secondary and Supersecondary Structures.-A Survey of Machine Learning Methods for Secondary and Supersecondary Protein Structure Prediction.-Beyond Supersecondary Structure: The Global Properties of Protein Sequences.-Creating Supersecondary Structures with BuildBeta.-A Modular Perspective of Protein Structures; Application to Fragment Based Loop Modeling.-Residue-residue Contacts: Application to Analysis of Secondary Structure Interactions.-Super-secondary Structures and Modeling of Protein Folds.-Computational Simulations of Protein Folding to Engineer Amino Acid Sequences to Encourage Desired Supersecondary Structure Formation.-Protein Folding at Atomic Resolution: Analysis of Autonomously Folding Supersecondary Structure Motifs by Nuclear Magnetic Resonance.-Artificial Supersecondary Structures Based on Aromatic Oligoamides.-Cross-b-sheet Super-secondary Structure in Amyloid Folds: Techniques for Detection and Characterization.-Analyzing Oligomerization of Individual Transmembrane Helices and of Entire Membrane Proteins in E. coli: A Hitchhiker´s Guide to GALLEX.-Super-secondary Structure Prediction of Transmembrane Beta-Barrel Proteins.-Functional Structural Motifs for Protein-ligand, Protein-protein and Protein-nucleic Acid Interactions and their Connection to Supersecondary Structures.