Quantitative Analysis in Nuclear Medicine Imaging / Edition 1

by Habib Zaidi

Overview

This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.

Product Details

ISBN-13:	9781441936684
Publisher:	Springer US
Publication date:	11/23/2010
Edition description:	Softcover reprint of hardcover 1st ed. 2006
Pages:	583
Product dimensions:	6.10(w) x 9.25(h) x 0.24(d)

Table of Contents

Overview of Nuclear Medical Imaging: Physics and Instrumentation.- Dual-Modality Imaging: More Than the Sum of its Components.- Analytic Image Reconstruction Methods in Emission Computed Tomography.- Iterative Reconstruction Methods.- Collimator-Detector Response Compensation in SPECT.- Attenuation Correction Strategies in Emission Tomography.- Scatter Correction Strategies in Emission Tomography.- Correction for Partial Volume Effects in Emission Tomography.- Image Registration Techniques in Nuclear Medicine Imaging.- Image Segmentation Techniques in Nuclear Medicine Imaging.- Monte Carlo Modeling in Nuclear Medicine Imaging.- Tracer Kinetic Modeling in Nuclear Medicine: Theory and Applications.- Methods for Planar Image Quantification.- Quantitative Analysis in Functional Brain Imaging.- Quantitative Analysis in Myocardial SPECT Imaging.- Quantitative Analysis in Nuclear Oncologic Imaging.- Quantitative Imaging-Based Dosimetry and Treatment Planning in Radionuclide Therapy.- Summary.

Editorial Reviews

Reviewer: Mark T. Madsen, PhD (University of Iowa Hospitals and Clinics)
Description: This book provides a recent survey on quantitative techniques in nuclear medicine that includes planar, SPECT and PET imaging. It also provides details on specific applications of these methods especially related to radionuclide treatment planning.
Purpose: The purpose is to provide a review of the methods required for quantitative nuclear medicine imaging and therapy. Quantitative nuclear medicine is a very important, sophisticated, and rapidly progressing field and there is a need for a book that combines recent information on physical compensation techniques and multimodality image analysis with current clinical applications. This book does exactly that.
Audience: It is clearly written for image scientists and graduate students interested in radionuclide imaging. The book is technically complete and includes the integral equations required to model the physical imaging processes, tomographic reconstructions, and tracer kinetics. Dr. Zaidi is an expert in this field and he has gathered together an outstanding group of eminent scientists to write about these issues. Dr. Zaidi is not only the editor, but is also author or coauthor of 12 of the 18 chapters. This gives the book a pleasing continuity and accounts for the consistency in presentation and equations.
Features: The book begins with a comprehensive review of the physics and instrumentation used in single photon and PET imaging. The next section covers information that any serious image scientist working in the field needs to know, including image reconstruction techniques, attenuation, scatter and spatial resolution compensation, and tracer kinetic modeling. Image segmentation and the registration of radionuclide volumetric data with other modalities are also covered along with a very useful summary of Monte Carlo and mathematical phantom resources. The final section focuses on clinical and therapeutic applications. Too often PET dominates discussions of quantitative radionuclide imaging at the expense of SPECT, but in this book there is a very nice balance between these two radionuclide imaging modalities. There are 110 illustrations and each chapter has an abundance of relevant and recent references.
Assessment: This is an outstanding book and it certainly belongs in the library of any serious imaging scientist.

Doody's Review Service

From the reviews:

"This book represents a timely tool, as it provides a general framework for understanding the basis of most quantitative approaches to NM imaging and for appreciating their pros and cons. … overall this book is easy to read, clear and stimulating. It can be recommended to all imaging professionals (NM physicians, residents and fellows, as well as physicists and engineers) who seek an authoritative guide that will enable them to keep up to date with the ‘hard’ quantitative aspects of NM … ." (Mario Quarantelli and Anna Prinster, European Journal of Nuclear Medicine & Molecular Imaging, Vol. 34, 2007)

"This book is intended primarily for physicists, physicians, imaging scientists, and graduate students who wish to obtain a high level of knowledge of image processing and analysis methods applied to quantitative nuclear medicine imaging in diagnosis and therapy. ... an excellent and up-to-date reference on advanced quantitative analysis methods applied to both single-photon and PET imaging. ... The book could also be used as a stand-alone text for a course on advanced topics in nuclear medicine imaging. I recommend this book ... ." (William D. Erwin, The Journal of Nuclear Medicine, Vol. 48 (8), 2007)

From the Publisher