The Power of Prions: The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases
Over the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson's and Alzheimer's-and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and the part they may have played in the beginnings of life on our planet.



Brahic, a leading researcher on diseases of the central nervous system, first describes the discovery of prions and their role in infection, beginning with early work on the animal disease scrapie and a mysterious human illness in New Guinea, apparently transmitted by cannibalism. Prion proteins were then revealed as the cause of other illnesses, from "mad cow" disease and its human counterpart, Creutzfeldt-Jakob disease, to such noninfectious brain disorders as Parkinson's and Alzheimer's. While the prion proteins responsible for diseases are definitively "bad," Brahic also explains that these abnormal prions are rare exceptions. Most of the time, prion proteins actually serve "good" and vital functions-and they may even have been present at the origin of life itself.
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The Power of Prions: The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases
Over the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson's and Alzheimer's-and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and the part they may have played in the beginnings of life on our planet.



Brahic, a leading researcher on diseases of the central nervous system, first describes the discovery of prions and their role in infection, beginning with early work on the animal disease scrapie and a mysterious human illness in New Guinea, apparently transmitted by cannibalism. Prion proteins were then revealed as the cause of other illnesses, from "mad cow" disease and its human counterpart, Creutzfeldt-Jakob disease, to such noninfectious brain disorders as Parkinson's and Alzheimer's. While the prion proteins responsible for diseases are definitively "bad," Brahic also explains that these abnormal prions are rare exceptions. Most of the time, prion proteins actually serve "good" and vital functions-and they may even have been present at the origin of life itself.
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The Power of Prions: The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases

The Power of Prions: The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases

by Michel Brahic

Narrated by Mike Cooper

Unabridged — 4 hours, 8 minutes

The Power of Prions: The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases

The Power of Prions: The Strange and Essential Proteins That Can Cause Alzheimer's, Parkinson's, and Other Diseases

by Michel Brahic

Narrated by Mike Cooper

Unabridged — 4 hours, 8 minutes

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Overview

Over the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson's and Alzheimer's-and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and the part they may have played in the beginnings of life on our planet.



Brahic, a leading researcher on diseases of the central nervous system, first describes the discovery of prions and their role in infection, beginning with early work on the animal disease scrapie and a mysterious human illness in New Guinea, apparently transmitted by cannibalism. Prion proteins were then revealed as the cause of other illnesses, from "mad cow" disease and its human counterpart, Creutzfeldt-Jakob disease, to such noninfectious brain disorders as Parkinson's and Alzheimer's. While the prion proteins responsible for diseases are definitively "bad," Brahic also explains that these abnormal prions are rare exceptions. Most of the time, prion proteins actually serve "good" and vital functions-and they may even have been present at the origin of life itself.

Editorial Reviews

From the Publisher

"Finalist for the PROSE Award in Biomedicine and Neuroscience, Association of American Publishers"

"Michel Brahic provides a thorough history of prion proteins that delves beyond their well-documented role in neurodegenerative diseases. A prion researcher himself, Brahic expertly details the origins of his field."—-Francisco J. Rivera-Rosario, The Transmitter

"Michel Brahic provides a close-up view of these mysterious proteins. . . . [and] provides a clear, straightforward overview of how the nervous system and proteins function."—-Ed Cara, Gizmodo

"Brahic writes succinctly about the science, and with feeling about people harmed by prion diseases."—-Meghan Rosen, Science News

"[The Power of Prions] delivers an exceptional contribution to the scientific literature. It helps increase the public’s understanding of complex scientific matters, pushing the boundaries of knowledge further in the realm of neurodegenerative diseases. Not only does it spotlight the fascinating world of prions, but it also provides a beacon of hope for anyone touched by these alarming diseases. By opening up the exploration of new and advanced treatments, the book rightfully earns its place on every informed reader’s bookshelf."—-Jonathan Antonio, Digital Chew

Product Details

BN ID: 2940192121184
Publisher: Tantor Audio
Publication date: 10/29/2024
Edition description: Unabridged
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