Understanding Glial Cells / Edition 1

by Bernardo Castellano, Berta González, Manuel Nieto-Sampedro

Overview

Understanding Glial Cells is a collection of selected works presented by Spanish research teams at the establishment and consolidation of the Spanish Glial Network in February 1997. Each of the work's four main sections, I) Morphology and Ontogeny, II) Molecular and Biochemical Properties, III) Involvement in Damage and Regeneration, and IV) Glia in Pathology, covers state-of-the-art research as it relates to glial cell biology. Within each of these sections, individual chapters introduce readers to advanced topics, present research results, and direct them to related research.
Understanding Glial Cells is not a basic text covering elementary topics but is meant for readers with a pre-existing interest in the field. The volume is especially suited for researchers, clinicians, and instructors in neurobiology, neurology or neuropathology, who want to improve their understanding of glial cells. In addition, medical and graduate students will find Understanding Glial Cells a useful reference volume.

Product Details

ISBN-13:	9781461376286
Publisher:	Springer US
Publication date:	10/11/2012
Edition description:	Softcover reprint of the original 1st ed. 1998
Pages:	434
Product dimensions:	6.10(w) x 9.25(h) x 0.04(d)

About the Author

Castellano, Bernardo, PhD; Gonzalez, Berta, PhD; Nieto-Sampedro, Manuel, PhD

Table of Contents

Preface. I: Morphology and Ontogeny. 1. Characterization of the Glial Cells in the Teleost Visual Pathway; J.M. Lara, et al. 2. The Macroglia of Teleosts: Characterization, Distribution and Development; S. Díaz-Regueira, R. Anadón. 3. Organization and Function of Astrocytes in the Human Retina; J.M. Ramírez, et al. 4. Astroglial Architecture of the Human Optic Nerve; Functional Role of Astrocytes; A. Triviño, et al. 5. Glial Cells Ontogeny in the Telencephalon and Mesencephalon of the Lizard Gallotia galloti; M. Monzón-Mayor, et al. 6. Role of Thyroid Hormone on the Oligodendrocyte Type 2-Astrocyte Lineage; A. Rodríguez-Peña, et al. II: Molecular and Biochemical Properties. 7. Characterization of Rat Neural Stem Cells from Embryonic Striatum and Mesencephalon During in Vivo Differentiation; E. Bazán, et al. 8. Expression of Neurotrophins and Their Receptors within Glial Cells of Retina and Optic Nerve; E. Vecino, et al. 9. Expression and Function of Neurotransmitter Receptors in Glial Cells of the Central Nervous System; C. Matute, et al. 10. Role of Astroglia in the Neural Effects of Sex Hormones and Neuroactive Steroids; M. del Carmen Fernández-Galaz, et al. 11. Cytokines and Astroglial Cells: Functions and Mechanisms of Action; F. Molina-Holgado, et al. 12. The Critical Factor for L-DOPA Toxicity on Dopamine Neurons is Glia; M.A. Mena, et al. III: Involvement in Damage and Regeneration. 13. Ethanol Exposure During Brain Development Alters Astrogliogenesis and Astrocyte Functions; J. Renau-Piqueras, etal. 15. Glial Response to Excitotoxic Injury in the Immature Brain; L. Acarín, et al. 16. Effects of Contralateral Lesions and Aging on the Neuronal and Glial Population of the Cerebral Cortex of the Rat; M.A. Peinado, et al. 17. The Role of Schwann Cell in Nerve Regeneration; E. Verdú, X. Navarro. IV: Glia in Pathology. 18. Glial Reactivity in Genetically Determined Disorders of Myelin; J.M. Vela, et al. 19. Glial Changes in Aging and Alzheimer's Disease; M.A. Morán, P. Gómez-Ramos. 20. Adhesion Molecules, Angiogenesis and Malignant Gliomas: Implications for Tumorigenesis; B. Conde, et al. Index.

Editorial Reviews

2 Stars from Doody

This book is a collection of selected works by Spanish glial research teams. The four main sections of the book: morphology and ontogeny; molecular and biochemical properties; involvement in damage and regeneration; and pathology include reviews and experimental findings on specific aspects of glial cell biology. The idea for this book arose from the establishment in 1997 of the Spanish Glial Network, a group of Spanish glial research teams. The objective is to present a compendium of work by these Spanish research teams focused on specific topics of interest in glial cell biology. These are worthy objectives, considering that much of the pioneering work on glia was by Spanish investigators such as Santiago Ramon y Cajal and Pio del Rio Hortega. These objectives are met by highlighting research from 70 Spanish contributors dealing with 20 particular aspects of glial cell biology. This book is directed to an audience with a pre-existing interest in the field, such as teachers, basic scientists and clinicians, and possibly medical and graduate students. The depth and breadth of the chapters are appropriate for this target audience. The editors are experienced in glial cell research. The first section focuses primarily on glial cell development and architecture in the visual system of teleosts, lizards, and humans; the second section includes differentiation, neurotrophins, neurotransmitter receptors, steroids, cytokines, and neurotoxicity; the third section discusses various lesion and regeneration models; the fourth section covers myelin disorders, aging and Alzheimer's disease, and gliomas. A strength is the excellent quality and visually appealing presentation of morphologicaland ultrastructural information. Other strengths are found in chapters that include both a general review and primary data. A particularly good example of this is the chapter on cytokines and astroglial cells. A shortcoming is that the topics are very narrow, with some areas (such as the visual system) receiving inordinate coverage and other topics (such as glial physiology, receptors, and neuronal-glial interactions) receiving very little attention. Other shortcomings include a number of typographical, grammatical, and numerical errors as well as somewhat outdated references. This book will not substitute for an in-depth glial reference book such as ""Neuroglia"" by Kettenmann and Ransom, nor will it replace a book with more extensive coverage of specific topics such as ""Astrocytes: Pharmacology and Function"" by Murphy. However, it is a useful reference for those interested in glial cell research in Spain.

Linda J. Van Eldik

Presents a compendium of 20 works by Spanish glial research teams. Chapters that constitute the four sections of this book are directed toward those researchers within neurobiology, neurology, or neuropathology with a pre-existing interest in the field, and discuss such subjects as the morphology and ontogeny of the cells, molecular and biochemical properties, involvement in neural damage and regeneration, and glia in pathology. Annotation c. by Book News, Inc., Portland, Or.

Booknews

Reviewer: Linda J. Van Eldik, PhD (Northwestern University Feinberg School of Medicine)
Description: This book is a collection of selected works by Spanish glial research teams. The four main sections of the book: morphology and ontogeny; molecular and biochemical properties; involvement in damage and regeneration; and pathology include reviews and experimental findings on specific aspects of glial cell biology.
Purpose: The idea for this book arose from the establishment in 1997 of the Spanish Glial Network, a group of Spanish glial research teams. The objective is to present a compendium of work by these Spanish research teams focused on specific topics of interest in glial cell biology. These are worthy objectives, considering that much of the pioneering work on glia was by Spanish investigators such as Santiago Ramon y Cajal and Pio del Rio Hortega. These objectives are met by highlighting research from 70 Spanish contributors dealing with 20 particular aspects of glial cell biology.
Audience: This book is directed to an audience with a pre-existing interest in the field, such as teachers, basic scientists and clinicians, and possibly medical and graduate students. The depth and breadth of the chapters are appropriate for this target audience. The editors are experienced in glial cell research.
Features: The first section focuses primarily on glial cell development and architecture in the visual system of teleosts, lizards, and humans; the second section includes differentiation, neurotrophins, neurotransmitter receptors, steroids, cytokines, and neurotoxicity; the third section discusses various lesion and regeneration models; the fourth section covers myelin disorders, aging and Alzheimer's disease, and gliomas. A strength is the excellent quality and visually appealing presentation of morphological and ultrastructural information. Other strengths are found in chapters that include both a general review and primary data. A particularly good example of this is the chapter on cytokines and astroglial cells. A shortcoming is that the topics are very narrow, with some areas (such as the visual system) receiving inordinate coverage and other topics (such as glial physiology, receptors, and neuronal-glial interactions) receiving very little attention. Other shortcomings include a number of typographical, grammatical, and numerical errors as well as somewhat outdated references.
Assessment: This book will not substitute for an in-depth glial reference book such as "Neuroglia" by Kettenmann and Ransom, nor will it replace a book with more extensive coverage of specific topics such as "Astrocytes: Pharmacology and Function" by Murphy. However, it is a useful reference for those interested in glial cell research in Spain.

Doody's Review Service