Viral Therapy of Human Cancers

by Joseph G. Sinkovics (Editor), Joseph Horvath (Editor)

Overview

Featuring contributions from nearly 30 leading authorities, this pioneering work gauges the potential for viruses to act as oncolytic and anti-tumor agents for the treatment of cancers in humans-detailing the cancer-combative properties exhibited by viruses in nature, genetically engineered viruses, and viral oncolysates as evidenced in basic and experimental studies.

Product Details

ISBN-13:	9780367393342
Publisher:	Taylor & Francis
Publication date:	12/13/2019
Pages:	848
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

Joseph G. Sinkovics , Joseph C. Horvath

Table of Contents

Introduction o Progressive Development of the Viral Therapy of Human Cancers: A Personal Narrative Account Joseph G. Sinkovics o New Biological Therapeutics: Competitors or Collaborators in Viral Therapy for Human Cancers Joseph G. Sinkovics o Naturally Oncolytic Viruses o Measles Virus: Improving Natural Oncolytic Properties by Genetic Engineering Christoph Springfield, Adele Fielding, Kah-Whye Peng, Eva Galanis, Stephen J. Russell, and Roberto Cattaneo o Newcastle Disease Virus: Anti-tumor Immune Memory and Its Activation for Control of Residual Tumor Cells and Improvement of Patient Survival Volker Schirrmacher o Newcastle Disease Virus: Its Oncolytic Properties Joseph C. Horvath o Influenza A Viruses with Deletions in the NS1 Gene: A Rational Approach to Develop Oncolytic Viruses Michael Bergmann and Thomas Muster o Vesicular Stomatitis Virus: An Oncolytic Agent Rebecca A. C. Taylor, Jennifer M. Paterson, and John C. Bell o Parvoviruses as Anti-Cancer Agents Jean Rommelaere, Nathalia Giese, Celina Cziepluch, and Jan J. Cornelis o Viral Oncolysates o Newcastle Disease Virus Oncolysate in the Management of Stage III (AJCC) Malignant Melanoma William A. Cassel, Douglas R. Murray, and Zbigniew L. Olkowski o Vaccinia Viral Lysates in Immunotherapy of Melanoma Peter Hersey o Genetically Engineered Oncolytic Viruses o Fusogenic Oncolytic Herpes Simplex Viruses for Therapy of Solid Tumors Xinping Fu, Mikihito Nakamori, and Xiaoliu Zhang o Poliovirus Recombinants Against Malignant Glioma Melinda Merrill, David Solecki, and Matthias Gromeier o Oncolytic Viruses that Depend on Loss of RB or p53 Frank McCormick