Williams Clinical Manual of Hematology / Edition 6

by Marshall Lichtman, Ernest Beutler, Thomas Kipps

Overview

A portable, quick-reference guide with clinical information on over 100 hematologic diseases and their management. Based on the Sixth Edition of Williams Hematology, the handbook presents concise information on etiology and pathogenesis, clinical and lab features, differential diagnosis, treatment, and prognosis.

Product Details

ISBN-13:	9780071399135
Publisher:	McGraw-Hill Companies, The
Publication date:	08/27/2002
Edition description:	REV
Pages:	560
Product dimensions:	5.50(w) x 8.50(h) x 1.39(d)

Table of Contents

	Preface	ix
Chapter 1	Approach to the Patient	1
Chapter 2	Supportive Care: Antimicrobials, Catheters, and Pain Control	9
Chapter 3	Pharmacology and Toxicity of Antineoplastic Drugs	19
Chapter 4	Classification of Red Cell Disorders	27
Chapter 5	Aplastic Anemia	29
Chapter 6	Pure Red Cell Aplasia	33
Chapter 7	Anemia of Chronic Renal Failure	37
Chapter 8	Anemia of Endocrine Disorders	39
Chapter 9	Congenital Dyserythropoietic Anemias	41
Chapter 10	The Megaloblastic Anemias	45
Chapter 11	Iron Deficiency Anemia	55
Chapter 12	Anemia Resulting from Other Nutritional Deficiencies	61
Chapter 13	Disorders of Iron Storage and Transport	65
Chapter 14	Hereditary and Acquired Sideroblastic Anemias	69
Chapter 15	Anemia Resulting from Marrow Infiltration	73
Chapter 16	Anemia of Chronic Disease	75
Chapter 17	Hereditary Spherocytosis, Elliptocytosis, and Related Disorders	77
Chapter 18	Hemolytic Anemia Related to Red Cell Enzyme Defects	87
Chapter 19	The Thalassemias	91
Chapter 20	The Sickle Cell Diseases and Related Disorders	99
Chapter 21	Hemoglobinopathies Associated with Unstable Hemoglobin	107
Chapter 22	Methemoglobinemia and Other Causes of Cyanosis	109
Chapter 23	Traumatic Hemolytic Anemia, March Hemoglobinuria, Sports and Space-Related Anemia	113
Chapter 24	Microangiopathic Hemolytic Anemia	117
Chapter 25	Hemolytic Anemia Resulting from a Physical or Chemical Agent	121
Chapter 26	Hemolytic Anemia Resulting from Infectious Agents	123
Chapter 27	Hemolytic Anemia Resulting from Warm-Reacting Antibodies	127
Chapter 28	Cryopathic Hemolytic Anemia	133
Chapter 29	Drug-Induced Hemolytic Anemia	137
Chapter 30	Alloimmune Hemolytic Disease of the Newborn	143
Chapter 31	Acute Blood Loss Anemia	147
Chapter 32	Hypersplenism and Hyposplenism	149
Chapter 33	The Polycythemias	155
Chapter 34	Hematologic Aspects of the Porphyrias	165
Chapter 35	Classification and Clinical Manifestations of Neutrophil Disorders	173
Chapter 36	Neutropenia and Neutrophilia	179
Chapter 37	Qualitative Disorders of Neutrophils	189
Chapter 38	Eosinophils and Their Diseases	199
Chapter 39	Basophils and Mast Cells and Their Diseases	205
Chapter 40	Monocytosis and Monocytopenia	209
Chapter 41	Inflammatory and Malignant Histiocytosis	211
Chapter 42	Lipid Storage Disease	217
Chapter 43	Classification and Clinical Manifestations of the Clonal Myeloid Disorders	221
Chapter 44	Clonal Cytopenias and Oligoblastic Leukemias (Myelodysplasias)	229
Chapter 45	Paroxysmal Nocturnal Hemoglobinuria (PNH)	233
Chapter 46	The Acute Myelogenous Leukemias	237
Chapter 47	The Chronic Myelogenous Leukemias	249
Chapter 48	Idiopathic Myelofibrosis (Agnogenic Myeloid Metaplasia)	259
Chapter 49	Classification of the Benign Lymphoid Disorders	265
Chapter 50	Lymphocytosis and Lymphocytopenia	269
Chapter 51	Primary Immunodeficiency Syndrome	275
Chapter 52	The Acquired Immunodeficiency Syndrome	279
Chapter 53	The Mononucleosis Syndromes	289
Chapter 54	Classification and Clinical Manifestations of the Malignant Lymphoid Disorders	295
Chapter 55	The Acute Lymphocytic Leukemias	303
Chapter 56	The Chronic Lymphocytic Leukemias	315
Chapter 57	Hairy Cell Leukemia	327
Chapter 58	Large Granular Lymphocytic Leukemia	333
Chapter 59	The Lymphomas	337
Chapter 60	Hodgkin Lymphoma	353
Chapter 61	The Monoclonal Gammopathies and Plasma Cell Dyscrasias	361
Chapter 62	Myeloma	367
Chapter 63	Macroglobulinemia	377
Chapter 64	Heavy-Chain Diseases	381
Chapter 65	Amyloidosis	383
Chapter 66	Clinical Manifestations, Evaluation, and Classification of Disorders of Hemostasis	387
Chapter 67	The Thrombocytopenias	395
Chapter 68	Essential Thrombocythemia and Thrombocytosis	415
Chapter 69	Hereditary Platelet Disorders	419
Chapter 70	Acquired Platelet Disorders	429
Chapter 71	The Vascular Purpuras	435
Chapter 72	Hemophilia A and B	441
Chapter 73	von Willebrand Disease	449
Chapter 74	Hereditary Disorders of Fibrinogen	457
Chapter 75	Inherited Deficiencies of Coagulation Factors II, V, VII, X, XI, and XIII and the Combined Deficiencies of Factors V and VIII and of the Vitamin K-Dependent Factors	461
Chapter 76	Hemostatic Dysfunction Related to Liver Diseases	469
Chapter 77	The Antiphospholipid Syndrome (Lupus Anticoagulants and Related Disorders)	471
Chapter 78	Disseminated Intravascular Coagulation	475
Chapter 79	Hyperfibrinolysis and Therapy with Antifibrinolytic Agents	485
Chapter 80	Thrombophilia	489
Chapter 81	Antiplatelet Therapy	495
Chapter 82	Anticoagulant Therapy	499
Chapter 83	Fibrinolytic Therapy	509
Chapter 84	Transfusion of Blood and Red Cells	513
Chapter 85	Transfusion of Platelets	521
Chapter 86	Therapeutic Hemapheresis	525
	Table of Normal Values	529
	Index	533

Editorial Reviews

Reviewer: Simrit Parmar, MD (Northwestern University Feinberg School of Medicine)
Description: This is an excellent, concise review of the important topics in hematology designed for use as a quick reference in the clinic and during hospital rounds. The language is easy to understand. The book is thorough and well organized and the information is reinforced with the help of tables and figures. The previous edition was published in 1996.
Purpose: The purpose is to provide a convenient and easy to navigate précis of pathogenetic, diagnostic, and therapeutic essentials of blood cell and coagulation protein disorders. The intent is to provide a book that is thorough and well organized and, at the same time, of a size that can be carried by the physician in the hospital or the clinic. These are very worthy objectives and essential in this field since it is impossible to remember all the facts of hematology.
Audience: The book is written for physicians/practitioners in the field of hematology, according to the author. In my opinion, it may be used by residents and fellows as well as clinicians. The authors are well established in the field of hematology and are considered authorities.
Features: The book covers disorders of red cells, white blood cells, and platelets including structural malformation, stem cell defects, and exogenous destruction. It addresses various kinds of anemia, hemoglobinopathies, porphyrias, neutropenias and their management, hematologic malignancies, and coagulation disorders. The best feature of the book is the way the precise and relevant information is delivered in an easy to read format. The red cell disorders are covered well. Of note is chapter 9 on congenital dyserythropoietic anemias, a difficult topic that is not easy to understand. The author has very elegantly described the whole syndrome in one and a half pages with the help of tables and figures. The only shortcoming is the lack of color photographs of the abnormal cells.
Assessment: This is an exceptional, high quality book. It is very practical and easy to use and understand. Because of its small size, it is easy to handle and can be carried around in the clinic and on hospital rounds. This book is exceptional compared to other books in the field that I refer to in my everyday practice, namely, Manual of Clinical Oncology, 4th edition, by Casciato and Lowitz (Lippincott Williams & Wilkins, 2000) and Handbook of Chemotherapy, 5th edition, by Skeel (Lippincott Williams & Wilkins, 1999). This new edition definitely justifies replacing the previous one since many new therapeutics have emerged and there have been rapid advances in our understanding of the pathophysiology of benign and malignant disorders of blood.

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4 Stars! from Doody