Dr. Robert Bruce Banner has led a life of endless struggling: struggling against the rampaging beast within that was spawned in the heart of a gamma bomb explosion; struggling with obsessed army officers like Major William Talbot, dedicated to hunting him down; struggling to provide his wife Betty with something akin to a normal life...a forbidding problem considering that Banner's intellect is presently trapped in the towering, hard-to-miss body of the incredible Hulk.

The persecution by the army, combined with Betty's unexpected pregnancy, prompts Bruce to take desperate measures. An experimental operation may hold the key to the cure he has long sought. It is a chance he will gladly take - and one that actually seems to pay off. But the risk may carry with it an unexpectedly high price, especially when the horrific secret of Betty's pregnancy is revealed. It's a price that puts Bruce and Betty's offspring at risk, and plunges the Hulk into the most terrifying and daunting exploit of his life, struggling against his greatest foes to save himself, his family, and his very soul.