Kathryn Drake is a Hunter for the Italian Directorate. She's been assigned to locate the Dagger of Cain, a dangerous artifact once thought to be only myth, before a group of brutal Vampires can use it to curse all of the Hunters. She is also tapped to locate and kill Dante Valentine, a one time Hunter turned vampire who also happens to be the one man she can't seem to keep her hands off. Can she find the relic and save the people she loves or will she be it's next victim?