Animal Models in Toxicology

by Shayne C. Gad (Editor)

Overview

Animal Models in Toxicology is a single-source reference for the use of animal models in toxicology. Chapters cover nine species used in toxicology and experimental biology. With contributions from experts in toxicology, toxicological pathology, and species-specific metabolism, each of these chapters provides an excellent introductory "course" alon

Product Details

ISBN-13:	9781040059883
Publisher:	CRC Press
Publication date:	04/05/2016
Sold by:	Barnes & Noble
Format:	eBook
Pages:	1152
File size:	9 MB

About the Author

Edited by

Shayne Cox Gad, PhD, DABT, is the principal of Gad Consulting Services in Raleigh, North Carolina. He has more than 38 years of broad-based experience in toxicology, drug, device development, document preparation, statistics, and risk assessment, having previously been the director of toxicology and pharmacology for Synergen, director of medical affairs technical support system services for Becton Dickinson, and senior director of product safety and pharmacokinetics for G.D. Searle. He is past president of the American College of Toxicology and Roundtable of Toxicology Consultants and a board-certified toxicologist. Dr. Gad has published 47 books and more than 350 chapters, papers, and abstracts.

Table of Contents

Introduction. The Mouse. The Rat. The Hamster. The Guinea Pig. Rabbit. The Ferret. The Dog. Primates. The Minipig. Alternative Species. Clinical Pathology of Laboratory Animals. Telemetry in Nonclinical Drug Safety Assessment Studies. Molecular Imaging Techniques in Laboratory Animals. Genetically Modified Animal Models. Model Selection and Scaling (Allometry). Susceptibility Factors. Laws, Regulations, and Guidelines for Animal Care and Use in Research. Necropsy and Gross Pathology. Immunology Laboratory Endpoints for Assessment of Immunomodulators in Preclinical Studies and Case Studies Using Anti-CD3 mAb in Cynomolgus Monkey

Editorial Reviews

"…should be in every toxicology laboratory that performs research involving animals. No other book … provides the same breadth and depth of information as found here…"
—Michele T. Pritchard, PhD, University of Kansas Medical Center in Doody’s Book Reviews

From the Publisher