Adaptive Systems in Drug Design

by Gisbert Schneider, Sung-Sau So

Overview

A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on its scientific merit alone.

Product Details

ISBN-13:	9781040195345
Publisher:	CRC Press
Publication date:	10/01/2002
Sold by:	Barnes & Noble
Format:	eBook
Pages:	169
File size:	6 MB

About the Author

Gisbert Schneider, Ph.D., Beilstein Professor of Cheminformatics, Institute of Organic Chemistry, Johann Wolfgang Goethe-University, Frankfurt, Germany. Sung-Sau So, Ph.D., F. Hoffmann-La Roche, Inc. Discovery Chemistry, Nutley, New Jersey, U.S.A.

Table of Contents

Foreword, Preface, 1. A Conceptual Framework, 2. Analysis of Chemical Space, 3. Modeling Structure-Activity Relationships, 4. Prediction of Drug-Like Properties, 5. Evolutionary De Novo Design; Epilogue