Basic Immunology E-Book: Basic Immunology E-Book

by Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD, Shiv Pillai MD, PhD

Overview

In this updated edition of Basic Immunology, the authors continue to deliver a clear, modern introduction to immunology, making this the obvious choice for today's busy students. Their experience as teachers, course directors, and lecturers helps them to distill the core information required to understand this complex field. Through the use of high-quality illustrations, relevant clinical cases, and concise, focused text, it's a perfectly accessible introduction to the workings of the human immune system, with an emphasis on clinical relevance.

• Concise, clinically focused content is logically organized by mechanism for efficient mastery of the material.
• Features an appendix of clinical cases and CD molecules.
• Includes numerous full-color illustrations, useful tables, and chapter outlines.
• Focus questions within each chapter are ideal for self-assessment and review.
• Key points bolded throughout the text make it easy to locate important information.

• Presents information in a format and style that maximizes usefulness to students and teachers studying medicine, allied health fields, and biology.
• Fully updated content equips you with the latest relevant advances in immunology.
• Revised and updated artwork enhances your visual learning of important principles and reduces the excessive factual details found in larger textbooks.
• Twelve brand-new animations available on Student Consult help further explain complex concepts.
• Student Consult eBook version included with purchase. This enhanced eBook experience gives you access to the text, figures, images, glossary of immunology terms, self-assessment questions, and references on a variety of devices.

Product Details

ISBN-13:	9780323400152
Publisher:	Elsevier Health Sciences
Publication date:	10/07/2015
Sold by:	Barnes & Noble
Format:	eBook
Pages:	344
File size:	39 MB
Note:	This product may take a few minutes to download.

About the Author

Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California

Table of Contents

1 INTRODUCTION TO THE IMMUNE SYSTEM,

Nomenclature, General Properties, and Components

2 INNATE IMMUNITY,

The Early Defense Against Infections

3 ANTIGEN CAPTURE AND PRESENTATION TO LYMPHOCYTES,

What Lymphocytes See

4 ANTIGEN RECOGNITION IN THE ADAPTIVE IMMUNE SYSTEM,

Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires

5 T CELL–MEDIATED IMMUNITY,

Activation of T Lymphocytes by Cell-Associated Antigens

6 EFFECTOR MECHANISMS OF T CELL–MEDIATED IMMUNITY,

Functions of T Cells in Host Defense

7 HUMORAL IMMUNE RESPONSES,

Activation of B Lymphocytes and Production of Antibodies

8 EFFECTOR MECHANISMS OF HUMORAL IMMUNITY,

Elimination of Extracellular Microbes and Toxins

9 IMMUNOLOGICAL TOLERANCE AND AUTOIMMUNITY,

Self-Nonself Discrimination in the Immune System and Its Failure

10 IMMUNE RESPONSES AGAINST TUMORS AND TRANSPLANTS,

Immunity to Noninfectious Transformed and Foreign Cells

11 HYPERSENSITIVITY,

Disorders Caused by Immune Responses

12 CONGENITAL AND ACQUIRED IMMUNODEFICIENCIES,

Diseases Caused by Defective Immunity

SELECTED READINGS,

APPENDIX I,

Glossary

APPENDIX II,

Cytokines

APPENDIX III,

Principal Features of Selected CD Molecules

APPENDIX IV,

Clinical Cases

INDEX,

Editorial Reviews

Reviewer:Marion C. Cohen, PhD(University of Medicine and Dentistry of New Jersey-NJMS)
Description:This compact book covers most of the major topics taught in basic immunology courses for medical and dental students. The material is presented in a very concise manner so that the level of detail is limited and some topics receive little attention. The most recent edition was published in 2006.
Purpose:The goal is to present a picture of how the immune system works in a way that allows students to learn basic principles without becoming bogged down in details that are more appropriately covered in advanced courses. Thus the book is limited to what the authors consider the key concepts of the field. Given the increase in information about the immune system, setting limits may be a good thing.
Audience:Medical students studying immunology during their preclinical years are the primary audience, but dental students could also use it.
Features:In addition to trying to cover the major topics that are taught in most medical immunology courses, this book focuses on human immune responses against infectious microbes. Factual details purposely have been limited. Although there are a few clinical cases presented in the appendix, immunologic diseases are presented in the chapters only to emphasize their relation to normal immune responses. Unfortunately, some topics are not covered. For example, there is little about the mucosal immune system, which is different from the peripheral immune system. The figures are presented well, but in some cases they are too complicated and condensed. (They are also available for use by faculty intheir presentations through Elsevier's Student Consult system.) There is also an extensive glossary and a list of the principal features of selected CD markers. At the end of each chapter is a list of review questions to reinforce the information that has been introduced.
Assessment:For some immunology courses, this is unquestionably an excellent choice. Other course directors and faculty might prefer a book with a bit more meat. Students will probably be happy with a book this size and it is certainly easy to read. Most importantly, immunology is a constantly changing discipline and this book is up to date.