Basic Science of PET Imaging

by Magdy M. Khalil (Editor)

Overview

This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and
its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.

Product Details

ISBN-13:	9783319400709
Publisher:	Springer-Verlag New York, LLC
Publication date:	11/07/2016
Sold by:	Barnes & Noble
Format:	eBook
Pages:	619
File size:	18 MB
Note:	This product may take a few minutes to download.

About the Author

Magdy M. Khalil Ph.D., Medical Biophysics, Department of Physics, Faculty of Science, Helwan University, Cairo, Egypt. 

Table of Contents

History.- Basics and Radiation safety of PET Imaging.- Chemistry of PET radiopharmaceuticals: labelling strategies.- PET radiopharmaceuticals in clinical and research domains.- Quality Control of PET radiopharmaceuticals.- Physiologic and Molecular basis of PET in Cancer imaging.- Basics and new developments of Cardiac PET imaging.- PET in preclinical arena: Instrumentation and applications.- Radiation Dosimetry of PET imaging.- Physics and instrumentation of PET and hybrid PET Imaging: focus on PET/CT.- Hybrid PET/MR Imaging: Technologic advances and clinical applications.- Quality control and quality assurance of PET Scanners.- Image quantification in PET Imaging.- Image processing and data analysis of PET and hybrid PET Imaging.- Partial volume correction in PET imaging.- Compartmental modeling of PET Kinetics.- Motion artefacts and correction techniques in PET/CT.- Role of PET/CT in radiotherapy treatment planning.

Editorial Reviews

This superbly edited book provides a broad overview of the current basic scientific principles underlying positron emission tomography (PET) and its preclinical and clinical applications in medicine. … Several groups should find this book educational and useful, including students, experienced clinicians, and stakeholders in radiology, nuclear medicine, molecular imaging, medical physics, health physics, patient safety, administration, regulatory bodies, professional organizations, and agencies.” (Lawrence T. Dauer, Doody's Book Reviews, May, 2018)

“Khalil and colleagues should therefore be commended for compiling such a comprehensive text swiftly enough for it to be contemporary. It wouldprovide an excellent grounding for a physicist, technologist, radiopharmacist or physician who has just entered the field. The clear print is illustrated with figures that really aid the readers’ understanding and are mostly of excellent quality, and in colour. … I would highly recommend this text … .” (Dr. Heather Williams, RAD Magazine, August, 2017)

From the Publisher