Bioactive Conformation I / Edition 1

by Thomas Peters

Overview

This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts – it is still valid and useful after 5 or 10 years. More information as well as the electronic version of the whole content available at: springerlink.com. The book will appeal to scientists and practitioners in the mentioned fields and in industry.

Product Details

ISBN-13:	9783540490777
Publisher:	Springer Berlin Heidelberg
Publication date:	02/21/2007
Series:	Topics in Current Chemistry , #272
Edition description:	2007
Pages:	309
Product dimensions:	6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

Spatial Screening for the Identification of the Bioactive Conformation of Integrin Ligands.- Dynamics and Thermodynamics of Ligand–Protein Interactions.- The Fibroblast Growth Factor (FGF) – FGF Receptor Complex: Progress Towards the Physiological State.- Characterization of Interactions Between Misfolding Proteins and Molecular Chaperones by NMR Spectroscopy.- NMR Analysis of Bioprotective Sugars: Sucrose and Oligomeric (1?2)-?-D-glucopyranosyl-(1?2)-?-D-fructofuranosides.- Residual Dipolar Couplings Report on the Active Conformation of Rhodopsin-Bound Protein Fragments.- Glycosyltransferase Structure and Function.- Exploiting Ligand and Receptor Adaptability in Rational Drug Design Using Dynamics and Structure-Based Strategies.

Editorial Reviews

From the reviews:

"Bioactive Conformation I contains eight chapters on quite different topics within the theme of the series. … it will be essential reading for any researcher working in any area that involves binding of a substance to a protein." (T. B. Grindley, Journal of the American Chemical Society, Vol. 130 (2), 2008)

From the Publisher