Darwin In the Genome: Molecular Strategies in Biological Evolution

Darwin In the Genome: Molecular Strategies in Biological Evolution

by Lynn Caporale
Darwin In the Genome: Molecular Strategies in Biological Evolution

Darwin In the Genome: Molecular Strategies in Biological Evolution

by Lynn Caporale

eBook

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Overview

Smart genomes--an enthralling account of revolutionary discoveries at the cutting edge of genomics research

Written by a molecular biologist at the forefront of genomics research, Darwin in the Genome is an exciting account of one of the hottest new theories in biology today: evolution by natural selection inevitably leads to strategic mutations. In the struggle for survival, from pathogens to flowers, birds to orangutans, baker's yeast to people, the fittest genomes are those that evolve effective molecular strategies that respond to, and in fact anticipate, challenges and opportunities in their environments.

Writing in a clear, accessible style, Lynn Caporale describes the emergence of genomic mutation strategies, which researchers are just beginning to uncover. She also spells out some of the more profound implications of these findings, including the importance of biodiversity, indeed human diversity, for survival, the possibility of bold new directions for medical research, and the inherent dangers of attempting to fix perceived "errors" in a human genome.


Product Details

ISBN-13: 9780071420518
Publisher: McGraw Hill LLC
Publication date: 10/30/2002
Sold by: Barnes & Noble
Format: eBook
Pages: 256
File size: 566 KB

About the Author

Lynn Caporale received her Ph.D. in molecular biology from the University of California at Berkeley. After teaching and doing research at New York University, Memorial/Sloan-Kettering Cancer Center, Rockefeller University, and Georgetown University, she moved to Merck Research Laboratories, where she spent over a decade focused on the discovery of new medicines. Dr. Caporale has held research and senior executive positions with various biotechnology companies and in the pharmaceutical industry and currently is an independent consultant in drug discovery and functional genomics. She lives in New York City.

Table of Contents

Prologue: Chance Favors the Prepared Genome Chapter 1: Diversity or Death Chapter 2: The Magic Staircase Chapter 3: Predators Battle Prey in the Genome Chapter 4: Mutation Is Not Monotonous Chapter 5: What the Antibody Genes Tell Us Chapter 6: Slippery DNA and Tuning Knobs Chapter 7: Everyone Has Something to Teach Us Chapter 8: The Genome Sends an SOS Chapter 9: Journeys through Space and Time Chapter 10: Strategies as Targets, Round One: The Pathogens Chapter 11: Strategies as Targets, Round Two: Cancer Chapter 12: Theme and Variations Chapter 13: Family Heirlooms: A Framework for Evolution Chapter 14: Interchangeable Parts Chapter 15: Jumping Genes Chapter 16: Be Prepared for the Unexpected Chapter 17: Mixing Up Genes for the Children Chapter 18: Sculpting the Genome Chapter 19: Decoding DNA Epilogue: What Became of the First Genome
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