Fluoroquinolone-Associated Disability (FQAD) - Pathogenesis, Diagnostics, Therapy and Diagnostic Criteria: Side-effects of Fluoroquinolones

by Stefan Pieper

Overview

In this book, Stefan Pieper supports doctors and therapists in easily diagnosing FQAD and in better and more adequately dealing with FQAD patients. 
Fluoroquinolones, as one of the most common and effective groups of antibiotics, are known to have a distinct spectrum of side effects. These adverse effects are rare in percentage terms, but frequent in absolute numbers due to the enormous quantities of prescriptions. Because they are usually quite severe and wide-ranging, they tend to run like a syndrome and have been classified by the FDA as a separate condition, the FQAD, because of their frequency, severity and risk of disability.
This book presents for the first time a comprehensive description and classification of the clinical picture and a proposal for a clinical diagnostic tool based on diagnostic criteria.

Product Details

ISBN-13:	9783030741730
Publisher:	Springer-Verlag New York, LLC
Publication date:	06/08/2021
Sold by:	Barnes & Noble
Format:	eBook
File size:	4 MB

About the Author

Dr. med. Stefan Pieper has been working in a practice for integrative medicine with a focus on mitochondrial medicine, acupuncture, nutrition and homeopathy for 25 years. During his time at the clinic, he worked for many years in internal medicine, anaesthesia and neonatal intensive care units. He is a paramedic and holds a British Diploma in Anaesthesia.

Dr. Pieper developed a diagnostic tool for the reliable detection of FQAD and he is one of the most experienced therapists in this field. With over 500 FQAD patients treated, he has an exceptionally high level of expertise.

Currently he is working together with the Centrum für Herz-, Kreislauf- und Gefäßmedizin, University of Berlin, Charité, on a study regarding the use of Fluoroquinolones and the risk of aortic aneurysm and dissection.

Table of Contents

1 Introduction to Fluoroquinolone-Associated Disability (FQAD).- 2 FQAD and Oxidative Stress and Mitochondrial Toxicity.- 3 FQAD and Musculoskeletal Damage / Collagen Disorder.- 4 FQAD and Neurotoxicity / Peripheral Neuropathy (PN) / Autonomic Neuropathy / Small Fibre Neuropathy.- 5 FQAD and Neuropsychiatric Adverse Effects.- 6 Diagnostic criteria of the FQAD.- 7 Inside Story - Practical experience with FQAD Patients.

Editorial Reviews

Reviewer: Vincent F Carr, DO, MSA, FACC, FACP (Uniformed Services University of the Health Sciences)
Description: This book discusses Fluoroquinolone-Associated Disability (FQAD), along with its pathogenesis, diagnostics, therapy, and diagnostic criteria.
Purpose: The author explains in the preface that the FDA established the term "Fluoroquinolone-Associated Disability" during an advisory meeting in 2015, but that the definition of the disability was not useful for treating physicians. This book's purpose is to explain the disability in a more practical way for clinicians.
Audience: This book is for practicing clinicians and anyone who has an interest in the Fluoroquinolone-Associated Disability diagnosis.
Features: The monograph is divided into seven chapters covering topics such as FQAD and oxidative stress/mitochondrial toxicity, FQAD and musculoskeletal damage/collagen disorder, FQAD and neurotoxicity/peripheral neuropathy (PN)/autonomic neuropathy/small fiber neuropathy, FQAD and neuropsychiatric adverse effects, and the diagnostic criteria of FQAD. Each chapter begins with a brief introduction followed by a description of the pathogenesis of the problem, the diagnostic aspects of the specific disorder, and the therapy. Each chapter is extensively referenced. The chapter on the diagnostic criteria of FQAD has a checklist for documenting the exposure to, length of exposure, symptoms and their impact on the patient's quality of life, and physical diagnoses associated with the disorder. The FQAD disability scale (adopted from Bell) is included to document the extent of the illness.
Assessment: This monograph describes the signs and symptoms of Fluoroquinolone-Associated Disability (FQAD) along with treatment options to document and monitor a patient with FQAD.

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