Handbook of Cell Signaling

by Ralph A. Bradshaw (Editor), Edward A. Dennis (Editor)

Overview

Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. - Contains over 350 chapters of comprehensive coverage on cell signaling - Includes discussion on topics from ligand/receptor interactions to organ/organism responses - Provides user-friendly, well-illustrated, reputable content by experts in the field

Product Details

ISBN-13:	9780080920917
Publisher:	Elsevier Science & Technology Books
Publication date:	11/03/2009
Series:	Cell Biology
Sold by:	Barnes & Noble
Format:	eBook
Pages:	3048
File size:	43 MB
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About the Author

Ralph A. Bradshaw: University of California, San Francisco Professor of Chemistry and Pharmaceutical Chemistry and Deputy Director of the Mass Spectrometry Facility; also Professor Emeritus of the Dept of Physiology & Biophysics, UC Irvine Bradshaw is an emeritus member of the Board of Directors of the Keystone Symposia on Molecular and Cellular Biology and Co-editor of Molecular and Cellular Proteomics. His research interests are in the area of polypeptide growth factors and their receptors, cell signaling, N-terminal processing of proteins and proteomics. He has published over 300 articles in these and related areas.
Edward A. Dennis: University of California, San Diego Distinguished Professor of Chemistry and Biochemistry and former Department Chair and Professor of Pharmacology in the School of Medicine, Dennis is currently Editor-in-Chief of the Journal of Lipid Research and Director of the LIPID MAPS initiative. He also served as Chair of the Board of Directors of the Keystone Symposia on Molecular and Cellular Biology and current as an Emeritus member of the Board of Directors. His current research focus is on phospholipases, cell signaling and lipidomics on which he has published over 300 papers, most related to signal transduction by lipid messengers

Table of Contents

Cell Signaling - Yesterday, Today and Tomorrow Initiation: Extracellular and Membrane Events Molecular Recognition Vertical Receptors Horizontal Receptors Membrane Proximal Events Transmission: Effectors and Cytosolic Events Protein Phosphorylation Transmission: Effectors and Cytosolic Events Calcium Mobilization Lipid-Derived Second Messengers Protein Proximity Interactions Cyclic Nucleotides G Proteins Developmental Signaling Nuclear Responses: Gene Expression and Translation Nuclear Receptors Transcription Factors Damage/Stress Responses Translational Control Events in Intracellular Compartments Cell-Cell and Cell-Matrix Interactions