Handbook of Transcription Factor NF-kappaB
Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is prov
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Handbook of Transcription Factor NF-kappaB
Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is prov
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Handbook of Transcription Factor NF-kappaB

Handbook of Transcription Factor NF-kappaB

Handbook of Transcription Factor NF-kappaB
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Handbook of Transcription Factor NF-kappaB

Handbook of Transcription Factor NF-kappaB

Overview

Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is prov

Product Details

ISBN-13: 9781040200568
Publisher: CRC Press
Publication date: 10/20/2006
Sold by: Barnes & Noble
Format: eBook
Pages: 232
File size: 3 MB

Table of Contents

Overview/Introduction. Structural Aspects of NF-kB/IkB. Regulation of IKK. Role of Ubiquitination/Proteolysis. Transcriptional Regulation/Chromatin. NF-kB in Innate Immunity. NF-kB in Adaptive Immunity. NF-kB in Inflammatory Diseases and Cancer. NF-kB in Genetic Diseases. Strategies for Inhibiting NF-kB. Methods in NF-kB Research.
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