Heal Thyself: A Doctor at the Peak of His Medical Career, Destroyed by Alcohol--and the Personal Miracle That Brought Him Back
368
Heal Thyself: A Doctor at the Peak of His Medical Career, Destroyed by Alcohol--and the Personal Miracle That Brought Him Back
368eBookFirst Edition (First Edition)
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Overview
Heal Thyself is the paperback edition of The End of My Addiction—a memoir of Ameisen's struggle and a call to action.
"[This book is] the story of the dazzling discovery of a cure that could soon be within reach of all . . . you must read this book." —David Servan-Schreiber, MD, PHD, author of Healing Without Freud or Prozac and Anticancer
When Olivier Ameisen's book was first published, Barbara Fisher noted in The Boston Globe that "this is not your usual memoir of addiction, degradation, and redemption." His story is indeed unusual—not because he was a brilliant cardiologist who developed a profound addiction to alcohol, or because he tried numerous treatment options and none helped. His story was the story of millions of alcoholics—until he decided to take his treatment into his own hands.
Searching for a cure for his deadly disease, he happened upon baclofen, a safe muscle relaxant that had recently shown promising results in studies with laboratory animals addicted to a wide variety of substances. Ameisen experimented with increasingly higher dosages until he reached a level that left him free of any craving for alcohol. That was more than six years ago.
In the past year, a growing number of researchers and doctors have been inspired by Ameisen and begun prescribing baclofen and lobbying for wide-scale studies into how the drug works. Last spring, no less an authority than the leading medical journal Alcohol and Alcoholism endorsed the book. Hailing Dr. Ameisen as "a remarkable medical researcher," it summed up its assessment strongly and directly: "This book is to be recommended."
Product Details
| ISBN-13: | 9781429933254 |
|---|---|
| Publisher: | Farrar, Straus and Giroux |
| Publication date: | 06/22/2010 |
| Sold by: | Macmillan |
| Format: | eBook |
| Pages: | 368 |
| File size: | 411 KB |
About the Author
Olivier Ameisen, MD, inaugurated the position of official physician to the prime minister of France. He came to the United States in 1983 to join the prestigious cardiology team at New York Hospital and Cornell University Medical Center, where he became an associate professor of clinical medicine and an associate attending physician. He is currently Visiting Professor of Medicine at the State University of New York Downstate Medical Center.
Olivier Ameisen, MD, inaugurated the position of official physician to the prime minister of France. He came to the United States in 1983 to join the prestigious cardiology team at New York Hospital and Cornell University Medical Center, where he became an associate professor of clinical medicine and an associate attending physician. He is the author of The End of My Addiction and Heal Thyself. He is currently Visiting Professor of Medicine at the State University of New York Downstate Medical Center.
Read an Excerpt
1. Moment of Truth
I CAME TO MY SENSES and took stock of where I was: in a cab, with blood streaming down my face and spattering my trench coat. I looked out the window and in the glow of the streetlights saw the cab was on Lexington Avenue in Manhattan, waiting for the light to change at 76th Street. The church on the corner reminded me it was Sunday, and I looked at my watch. It was almost midnight. The few people on the street were buttoned up against the late winter chill, but it was warm in the cab.
My apartment was not too far away, on East 63rd Street between York and First Avenues, but I needed medical attention. I asked the driver to take me to the emergency room at New York Hospital, at 68th Street and York Avenue. He seemed oblivious to my condition, and I wondered what had happened. Had the cab braked suddenly so that I hit my head, or had I been injured in some other way before I hailed it? I knew I’d been drinking, but not where or how much.
As the cab pulled up in front of the hospital emergency room entrance, a memory of the evening began to come together. Around 8:30 p.m. I had visited my friend Jeff Steiner, the CEO of Fairchild Corporation, to ask his advice on running my cardiology practice, which I’d started two and a half years before. I’d been introduced to Jeff in the late 1980s by a mutual friend, another physician.
Although I’d intended not to drink that evening, I felt insulted when Jeff’s butler offered me a choice of teas. "Why doesn’t he offer me an alcoholic drink as well at this hour?" I thought. "Is this a judgmental message?"
I asked for and drank a glass of Scotch, then made a show of declining a refill. Much later I learned that Jeff was not aware that I had been drinking heavily. He’d known me only to have a few drinks at large parties, here and there, over the years. But my mounting concerns about my practice finances had changed that.
The standard expectation is that it will take a new medical practice two years to break even. Mine broke even in four months. And almost three years later, in March 1997, there it remained— hovering a little over the break-even point.
Staggering into the emergency room, I thought, "They will see I’m drunk. That’s not so good. But at least I know the place is well run and will fix me up right." I had been associated with New York Hospital and its partner institution, Cornell University Medical College,* ever since I arrived from France in the fall of 1983 to do research and clinical fellowships in cardiology. Thirteen and a half years later, I was a clinical associate professor
*As the two institutions were then known; in 1998 they became New York-Presbyterian Hospital and Weill Cornell Medical College.
of medicine at Cornell and an associate attending physician at New York Hospital, in addition to running my private practice.
Inside the emergency room, I passed out again. When I came to, one of my ex-students, Matt, now a resident, was standing over me preparing to stitch the wound in my forehead. So as not to be left with a scar, I asked him to use Steri-Strips instead. He did and then left me to lie quietly for a few hours so I could sober up enough to walk home safely. He was plainly even more embarrassed to treat me in my drunken state than I was to need treatment. I cringed at the thought of my appearance in the ER being discussed around the hospital, then pushed the thought out of my mind. Matt was not the kind of person to talk about it; that was some comfort.
Lying there, I ran the video of the evening in my mind. "Run the video of what happens when you drink" was something I’d been hearing in Alcoholics Anonymous, where I was still very much a newcomer.
My conversation with Jeff Steiner had been frustrating for us both. Although he was eager to help, there was a mismatch between his expertise and my problems. What I really needed was a small business adviser, not a big corporate dealmaker.
As I left Jeff’s apartment, my mind whirled with conflicting thoughts. My cost-blind practice style might function better in France’s universal health care system than in the United States, I thought, and I wondered if I should relocate back to Paris, where I was from. But I loved my life in New York. In 1991 I had acquired U.S. citizenship, and it pleased me to be a citizen of a country with so many shared ideals with my country of origin. If not profitable, my practice was at least busy and my work enormously rewarding. My patient roster included wealthy andcelebrated people along with Harlem church ladies on Medicare or Medicaid and the indigent, and I liked that mix. And my social life was wonderfully stimulating—more so than I could imagine having anywhere else. No, I wasn’t eager to leave.
But my practice could not continue indefinitely at this rate, and the constant anxiety created by financial worries was growing into a source of full-blown panic. I struggled with a deep sense of failure, and I lived in fear that the world would see that my accomplishments were nothing but a sham, a house of cards that could collapse at any second.
This was not a new feeling to me. Throughout my life I had been plagued by anxious feelings of inadequacy, of being an impostor on the brink of being unmasked. I had been seeing therapists for a long time before I started drinking. To be honest, they never were much help with my anxiety. Nor was the Xanax they prescribed me.
The one Scotch at Jeff’s made me aware of how thirsty I was. I went to a Chinese restaurant, intending to have a meal as well, but wound up eating nothing and drinking one double vodka after another. And then . . . I found myself bleeding in the taxicab.
It wasn’t my first blackout drinking. But the blackouts were getting more common, whole stretches of evenings expunged from my memory. And this was the first time I’d come out of a blackout with a physical injury. Until then blackouts had only been sources of intense mortification as I wondered what embarrassing things I might have said or done.
The next morning I thought briefly about amusing tales I could concoct to explain the bandages on my forehead. Decidingthat I was too hungover to go to work, I had my office assistant reschedule the day’s patients. As my drinking had increased, I had scrupulously honored my first duty as a doctor—to do no harm. I stopped driving. And I never set foot in my office or the hospital when I was not completely sober.
Still, I resisted seeing myself as a problem drinker. All I really needed, I thought, was to learn to drink better. This delusion was encouraged by a well-meaning friend and an equally well-meaning but I think even more misguided therapist, both of whom undertook to show me how to be a moderate wine drinker rather than a binger on Scotch or vodka. I even began AA with the thought that it might give me tips on managing my drinking better rather than stopping completely.
Not everyone thought I was a candidate for moderation. The two friends who escorted me to my first meeting didn’t think so. One was a longtime AA member, a poet and a writer and a very beautiful woman who looked a bit like Katharine Hepburn. She used to say, "I want you to see me before I lose my looks." She still has those looks today. When we met, she had been sober for many years, yet she told me, "I am an alcoholic." That struck me as very strange, and I was embarrassed to hear her say it. People with diabetes or hypertension didn’t identify themselves by their illnesses. Why should people with alcoholism?
Of course, I thought that because I did not want to admit— to myself or anyone else—that I might be alcohol-dependent. And so I was terrified to go to a meeting. But my friends each took me by an arm, and escorted me from my apartment on East 63rd Street to the major AA meeting place in the neighborhood— the 79th Street Workshop, in the basement of St. Monica’s Catholic Church, on 79th Street between York and First Avenues. Itwas my first step, taken reluctantly, toward facing my illness. But it was a vital one.
It is hard for everyone who attends AA to get past the potential embarrassment of being seen as an alcoholic. Shortly before I went to AA for the first time, my shrink began encouraging me to go. I said, "What about anonymity? My office and my apartment are right in the same neighborhood. What if a patient or somebody else I know sees me?"
He said, "Don’t worry. Anyone inside will be an alcoholic and won’t say anything."
"But what if a colleague sees me entering or leaving the place?"
"It won’t happen."
It did happen. But after I started going to AA, I told him, "AA is a great place. Have you been to a meeting?"
"No."
"You refer people. Maybe you should know what it’s like. Will you come with me to an open meeting?"
"No."
"Why not?"
"Because somebody might see me."
There is a moral stigma to addiction, and it is prospective shame that drives people to resist admitting they have a problem. It leads physicians to miss or delay a diagnosis of addiction, too. Only a couple of months earlier, I had brought up AA in a session with my shrink. "Oh, you’re not an alcoholic," he said dismis-sively, "but you could become one." Then he changed the subject away from alcohol and drinking.
Later on in my alcoholism, when I knew more about the course of the illness, I wondered how he could have missed the signs of its onset in me, and could even have turned a deaf ear to my first outright call for help. The responses of my physician colleagues at New York Hospital–Cornell puzzled me, too. When I would discreetly ask around about how to help "someone" with a drinking problem, they’d ask, "Is the person close to you?"
If I said no, they’d say, "You don’t want to get involved. It’s a minefield."
If yes, "Well, I really don’t know what to say. It’s very complex . . ."
Recent studies have shown that, at least among physicians who are not specialists in the field, a missed or delayed diagnosis is the rule, rather than the exception, in cases of addiction. One study videotaped doctors and patients and found that when patients mention addiction issues, doctors tend to change the subject as quickly as possible.1
I didn’t know what to make of this phenomenon when I first encountered it. But it has dawned on me that doctors are uncomfortable with the subject because they don’t have a reliable treatment to deliver or recommend.
The lack of reliable treatment also explains the moral assumptions attached to addiction. Whenever medicine has lacked a means to cure an illness, it has blamed the patient’s lack of moral virtue, positive thinking, and willpower. In the nineteenth century, tuberculosis was associated in novels and operas with characters of dubious morality or sanity, at least insofar as the establishment was concerned. Think of Fantine, the unwed mother turned prostitute in Victor Hugo’s Les Misérables; thederanged revolutionary Kirillov in Dostoevsky’s The Possessed; or the courtesan Violetta in Verdi’s La Traviata. Susan Sontag memorably exposed a similar dynamic at work in relation to cancer and AIDS, respectively, in Illness as Metaphor and AIDS and Its Metaphors.
I very much feared moral judgments about my drinking, and no one was judging me more harshly than me. "I am supposed to be an intelligent person with willpower. I should be able to control my urge to drink. When people find out about my drinking, they will finally see what a fake I am," I told myself.
What further complicates the picture is the fact that some people are able to halt their compulsive behavior with the help of twelve-step programs like AAand commonly prescribed medications like Revia, Campral, and Antabuse. But for the vast majority of people with addiction, these are not enough. They weren’t for me. Which is not to say that AA didn’t help me. It did. It was a critical resource without which I might not have survived until I found an effective medication in baclofen. It taught me a great deal about accepting my illness and about my fellow sufferers and myself, but it couldn’t stop my cravings or the uncontrollable anxiety that led me to drink.
I was terrified of living without alcohol. Without it, I would be an anxious wreck. Admitting my problem drinking to most of my friends and my colleagues terrified me, too. I feared being ostracized, and since I felt that drinking should be under my control I felt ostracism would be justified. (Naively, I assumed that very few physicians had a drinking problem. I didn’t yet know that about 10 percent of physicians, like roughly 10 percent of the general population, will become dependent on alcohol at some point in their lives, that many more in each group are prob-lem drinkers, and that according to the British Medical Association, physicians are three times more likely than the general population to have liver cirrhosis from alcohol abuse.)2
Through the next two months after my appearance in the ER, I clung to abstinence. I called my new AA sponsor regularly, and worked overtime in my practice so that I had no free time for drinking. And in June, I went off to the Swiss Alps, which, since my childhood, had been a magical place for me. But hiking in the mountains and quiet evenings after a good dinner failed to restore my spirits as usual. I had been sober for sixty-three days, but there was no peace in me. My drinking had threatened my career, even my life. I needed to talk to someone about it.
I decided to call André Gadaud, whom I’d met in 1984 when he became France’s consul general in New York. After other high-level diplomatic postings, André had become the French ambassador to Switzerland. He was also what they call in AA a "civilian," that is, a non–problem drinker. We’d always had a great rapport, and I thought sharing my secret with him might help me.
André generously offered to drive from the French embassy in Bern and meet me for lunch at the Hotel Quellenhof in Bad Ragaz, a luxurious thermal resort town. As we sat down to lunch, André said, "Let’s order champagne and have a toast, since we haven’t seen each other in several years."
"I’d rather not have champagne," I said.
"Why not? It’s been so long!"
I did not know how to say no, so I gave in. It felt impossible to refuse champagne when it was proposed by a French ambassador, and then it felt equally impossible to reveal that my drinking had become a serious issue. I worried that André would assumeI was not exercising enough willpower and lose respect for me. It seemed better to keep quiet and not risk ruining our visit or possibly even our friendship.
After lunch, during which I restricted myself to only one glass of champagne, André and I walked for hours in the mountains, talking about everything except my problem, before he had to drive back to Bern. That evening, I went to a pizzeria for dinner. When the waiter asked if I wanted a drink, I immediately started craving alcohol. The glass of champagne at lunch had reactivated the whole cycle, which I knew would be hard to fight.
The craving became stronger, growing in my chest, in my throat. Some cravings are more violent than others. Although cravings have an emotional component, the physical part was the hardest to bear for me. An AA acronym, HALT, sums up the states—Hungry, Angry, Lonely, Tired—in which cravings strengthen. I was experiencing all four. I was jet-lagged, lonely and angry because my friend had left without my being able to mention why I had called, and hungry because my food was very slow to arrive.
Just to take the edge off, I ordered a double vodka tonic, assuring myself that a single drink would forestall a major binge. It almost worked. After dinner, I felt somewhat soothed. But as I walked back to the hotel, I passed a bar and the craving struck again with irresistible force.
I entered the bar and ordered a double vodka tonic. Another customer came over. "I heard you play the piano here last summer," he said. "You were terrific. Would you please play again?"
Excerpted from Heal Thyself by Olivier Ameisen.
Copyright © 2009 by Olivier Ameisen.
Published in 2009 by Farrar, straus and giroux.
All rights reserved. This work is protected under copyright laws and reproduction is strictly prohibited. Permission to reproduce the material in any manner or medium must be secured from the Publisher.
Reading Group Guide
Questions for Discussion
1. The book's narrative weaves together a personal and a scientific story. Did you find the combination of these elements effective and compelling? What was the most powerful personal moment in the book for you? What part of the science of addiction most intrigued you?
2. The book reports that 1 in 4 U.S. deaths is caused by alcohol, tobacco, or illegal drugs, and observes that addiction to nicotine is the single biggest cause of cancer. Were you aware that addiction is such a huge public health problem? Would you support changing public health priorities to provide more funding for addiction research and treatment?
3. The rates of alcoholism and illegal substance dependence among physicians equal those in the general population. Based on what you've read in the book, do you think medical and governmental authorities are taking the right measures to identify and treat physicians with substance-dependence problems, in order to help them and safeguard the public?
4. Dr. Ameisen describes how the moral stigma of addiction pervades our society, despite overwhelming evidence that addiction is a biological disease that manifests itself in imbalanced neurotransmission in the brain. Studies cited in the book also show that the likeliest explanation for vulnerability to addiction is a preexisting imbalance in neurotransmission associated with chronic anxiety and depression, post-traumatic stress disorder, or related problems. Before reading the book, were you inclined to see addiction as a failure of moral character or self-control? Has reading it changed your view of addiction and those who suffer from it?
5. Dr. Ameisen explores the possibility that his mother's traumatic experiences as a Holocaust survivor may have predisposed him to chronic anxiety and thus made him vulnerable to addiction. Have you observed similar patterns in your own family or in friends' families?
6. Addiction has both direct and indirect victims— not only alcoholics and other addicts, but also their families, loved ones, and friends. Has the book deepened your understanding of how the disease drives a wedge between the people who suffer from it and those around them? After reading it, do you feel any better equipped to reach out to a friend, relative, or coworker who is struggling with substance dependence?
7. As the book explains, studies show that people with anxiety, depression, and post-traumatic stress disorder or with so-called nondrug addictions—gambling addiction, binge eating, sex addiction, and compulsive shopping, among others— have the same imbalanced neurotransmission as people with drug addictions. Given this shared pattern, does it seem reasonable that a single medication might be effective against all these problems?
8. The history of medicine reveals that whenever medicine has lacked an effective treatment for an illness, it has blamed the patient for supposed immorality or a lack of positive attitude and willpower. Were you surprised to read in the book that victims of tuberculosis and cancer were once seen in this way? What can each of us do to change the way addiction is viewed by society?
9. The book reports studies documenting that doctors most often miss the signs of addiction in their patients, and even change the subject when patients bring it up. What should be done to encourage honest discussion between doctors and patients about addiction?
10. Serendipity—a lucky break—made Dr. Ameisen aware of baclofen, and many other important medical and scientific breakthroughs have depended on chance. Has luck ever played such a dramatic role in your own life? Do you think medical and scientific authorities are as open to serendipity as they should be?
11. When Dr. Ameisen first heard about baclofen and began self-experimenting with it, he did not know how safe it was. What do you think of his decision, as a patient and a physician, to prescribe himself baclofen?
12. After baclofen ended Dr. Ameisen's craving for alcohol and completely freed him from addiction, he was astonished to learn that neurologists have safely used high doses of baclofen for comfort care of patients with muscular spasms and similar problems since the 1960s, but that largely because of the specialization of modern medicine, addiction researchers and caregivers did not know anything about this. What should medical authorities and organizations do to encourage doctors in different fields to learn from one another?
13. Baclofen has been documented to be non-euphoric and nonaddictive. Do you agree with Dr. Ameisen that taking baclofen for addiction should be seen in the same way as taking a medication for any chronic condition, such as a beta-blocker for high blood pressure?
14. Before he found baclofen, Dr. Ameisen tried every available form of treatment for alcoholism. But as the book discusses, the existing treatments are not enough on their own to help the vast majority of alcoholics and other addicts to quit. Given the extremely high failure rate of existing treatments, and in light of baclofen's excellent safety record and documented effectiveness in both animals and humans, do you think addiction specialists' resistance to prescribing baclofen is reasonable?
15. Following Dr. Ameisen's example and treatment protocol, some other physicians are already prescribing baclofen to alcoholics and other addicts. Is this a good thing, or should more studies be done first?
16. The usual medications for addiction—disulfiram, naltrexone, acamprosate, topiramate, and varenicline—have shown only limited benefit in repeated trials, and all except acamprosate can have serious side effects. What do you think of pharmaceutical companies that continue to push these medications, and of doctors who continue to prescribe them? What is your reaction to seeing advertisements for these medications?
17. Prescribing baclofen for addiction is an "off-label" use. Before reading the book, did you know that more than 23 percent of all prescriptions are off-label? Has a physician ever advised you that he or she is prescribing something to you or a family member off-label?
18. A randomized clinical trial of baclofen for addiction would cost about $500,000. Because baclofen is out of patent and has been available as a generic prescription medication since the 1980s, no pharmaceutical company has a financial incentive to fund such a trial. Given the enormous cost to society of treating substance abuse—alcohol abuse–related costs have been estimated at $200 billion a year in the U.S. alone—should government step in to fund randomized clinical trials of baclofen?
19. Dr. Ameisen observes that AIDS activists had a decisive influence on changing AIDS treatment to incorporate lifesaving medications, and he calls on patients, their families, and concerned physicians to lobby for clinical trials of baclofen for addiction. How much influence do you feel patients with addiction and their advocates should have on the direction of medical research and treatment?
20. A bill is pending in Congress to change the name of the National Institute on Drug Abuse to the National Institute on Diseases of Addiction and the name of the National Institute on Alcohol Abuse and Alcoholism to the National Institute on Alcohol Disorders and Health. As the book discusses, many scientists and physicians support this as part of the new understanding of addiction as a biological disease, but others criticize it as diminishing the importance of personal responsibility in recovery from addiction. Before reading the book, would you have supported the name changes? Has reading the book changed your opinion?