Introduction to Functional Magnetic Resonance Imaging: Principles and Techniques

by Richard B. Buxton

Overview

Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.

Product Details

ISBN-13:	9780511699474
Publisher:	Cambridge University Press
Publication date:	08/27/2009
Sold by:	Barnes & Noble
Format:	eBook
File size:	9 MB

About the Author

Richard B. Buxton is Professor of Radiology and Director of Magnetic Resonance Research at the University of California at San Diego.

Table of Contents

Part I. An Overview of Functional Magnetic Resonance Imaging; Section 1. Introduction to the Physiological Basis of Functional Neuroimaging: 1. Neural activity and energy metabolism; 2. Cerebral blood flow and brain activation; Section 2. Introduction to Functional Magnetic Resonance Imaging: 3. Nuclear magnetic resonance; 4. Magnetic resonance imaging; 5. Imaging functional activity; Part II. Principles of Magnetic Resonance Imaging; Section 1. The Nature of the Magnetic Resonance Signal: 6. Basic physics of magnetism and NMR; 7. Relaxation and contrast in MRI; 8. Diffusion and the MR signal; Section 2. Magnetic Resonance Imaging: 9. Mapping the MR signal; 10. MRI techniques; 11. Noise and artifacts in MR images; Part III. Principles of Functional Magnetic Resonance Imaging; Section 1. Perfusion Imaging: 12. Contrast agent techniques; 13. Arterial spin labeling techniques; Section 2. Blood Oxygenation Level Dependent Imaging: 14. The blood oxygenation level dependent effect; 15. Design and analysis of BOLD experiments; 16. Interpreting the BOLD response; Appendix. The physics of NMR.

Editorial Reviews

3 Stars from Doody

Reviewer: Michael Schrift, DO (University of Washington School of Medicine)
Description: This is the second edition of a useful introductory book on a technique that has revolutionized neuroscience, specifically cognitive neuroscience. Functional magnetic resonance imaging (fMRI) has now become the standard tool for studying the brain systems involved in cognitive and emotional processing. It has also been a major factor in the consilience of the fields of neurobiology, cognitive psychology, social psychology, radiology, physics, mathematics, engineering, and even philosophy. Written and edited by a clinician-scientist in the field, this book remains an excellent user's guide to this new technology.
Purpose: The goal, according to the author, is "to provide a guide to the principles of fMRI in research, but also to make the material accessible to the new investigator or clinician with no prior knowledge of the field." Indeed, the author has produced a very helpful and now updated introduction to the field.
Audience: The targeted audience is researchers who use fMRI, which now involves a multitude of disciplines. Clinicians would also benefit from reading this book.
Features: Part 1 is an overview of fMRI and its chapters cover neural activity and energy metabolism as well as cerebral blood flow and brain activation. Part 2 summarizes the principles of fMRI and the nature of the MR signal. Perfusion mapping and BOLD imaging are covered in the third part of the book. The appendix covers the physics of nuclear magnetic resonance. The index is detailed and helpful. Each chapter concludes with timely and relevant citations of the scientific literature.
Assessment: This is an excellent introduction to a field that is revolutionizing the brain sciences. I highly recommend it to clinicians who would like to keep abreast of this paradigm-changing technology.

Doody's Review Service

"This is an excellent introduction to a field that is revolutionizing the brain sciences. I highly recommend it to clinicians who would like to keep abreast of this paradigm-changing technology."
Doody's Review Service

"In this extensive book on the subject by Richard B. Buxton, a physicist by background and a leading authority on fMRI, you - the student, resident, or fellow in neuroimaging, or even the clinician, researcher or experienced neuroscientist - can study, understand a lot of neurological processes … The information in the chapters of this book is presented with a lot of visuals to facilitate your understanding of the various complex topics."
Biz India

From the Publisher