Joint and Bone: From Bench to Bedside

by Deming Jiang (Editor), ACUE El-Hashash PhD (Editor)

Overview

Joint and Bone: From Bench to Bedside, Volume Three, the latest release in the Stem Cell Innovation in Health and Disease series, is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. This new volume addresses the molecular players underlying iPSC formation, maintenance, and expansion and differentiation, bringing chapters that describe cutting-edge research for understanding stem cell functions in joint and bone diseases, and for developing methods to bring stem cells from bench to bedside. Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases. - Provides cutting-edge research needed to understand stem cell functions in joint and bone diseases - Develops processes to bring stem cells from bench to bedside - Includes up-to-date references on stem cell biology and function in the joint and bone

Product Details

ISBN-13:	9780323983303
Publisher:	Elsevier Science & Technology Books
Publication date:	01/30/2023
Series:	Stem Cell Innovation in Health & Disease
Sold by:	Barnes & Noble
Format:	eBook
Pages:	246
File size:	10 MB

About the Author

Dr. Gemn Jiang is an Associate Professor at the Zhejiang University School of Medicine. Professor Jiang has committed himself to scientific research in the field of sports system injury and regeneration. He has identified a new tendon differentiation model and recovered new mechanisms of tendon differentiation, as well as fabricated a functional tendon scaffold. Based on this work, he gained YIA of the international tendon/ligament conference in 2010. He also gained the second prize of the Natural Science Award of ministry of education.
Dr. Ahmed Hashash is currently Endowed Chair and Distinguished Professor at Elizabeth City State University, campus of the University of North Carolina (UNC). He received his PhD from Manchester University, UK. Dr. Hashash was a fellow of the California Institute of Regenerative Medicine (CIRM) and New York University Medical School (MSSM), USA. He was Assistant Professor and Principal Investigator of Stem Cell & Regenerative Medicine at School of Medicine University of California, USA. Dr Hashash was Associate Professor of Biomedicine at the University of Edinburgh (UK) Zhejiang Intl. campus and Texas A &M University, USA from 2017 to 2025. He has published more than 40 papers in reputed international journals, 10 books with Elsevier and Springer and over 20 book chapters, and is serving as an editorial board member of repute.

Table of Contents

1. Cutting edge research on stem cell applications in joint and bone repair and regeneration2. Stem Cell-Based Organoid culture system as innovative model of osteoarthritis and other joint/bone diseases3. Contributions of stem cell engineering to new therapies of joint/bone diseases4. Roles of innovative genome editing technologies (e.g. CRISPR/Cas9 systems) in stem cell engineering, rheumatic diseases and other joint/bone diseases5. Preclinical and clinical applications of iPSC technology in modeling osteoarthritis pathologies and testing drugs6. The gold standard iPSCs in cartilage, joint and bone repair and regeneration7. Mesenchymal stem cell related therapies for cartilage, joint and bone diseases8. Advances in animal models for joint and bone diseases9. Novel Biomaterials for stem cell engineering and bone regeneration10. General Discussion, Conclusion Remark and Future Direction

What People are Saying About This

From the Publisher

Overviews the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics in the joint and bone