Large-Scale Mammalian Cell Culture Technology

by Lubiniecki

Overview

An interdisciplinary approach, integrating biochemistry, biology, genetics, and engineering for the effective production of protein pharmaceuticals. The volume offers a biological perspective of large-scale animal cell culture and examines diverse processing strategies, process management, regulator

Product Details

ISBN-13:	9781351435703
Publisher:	CRC Press
Publication date:	05/02/2018
Series:	Biotechnology and Bioprocessing
Sold by:	Barnes & Noble
Format:	eBook
Pages:	656
File size:	10 MB

About the Author

Anthony S. Lubiniecki

Table of Contents

Series Introduction, Series Introduction, Contributors, 1: Large-Scale Mammalian Cell Culture: A Perspective, 2: Use of Recombinant DNA Technology for Engineering Mammalian Cells to Produce Proteins, 3: Large-Scale Animal Cell Culture: A Biological Perspective, 4: Mammalian Cell Physiology, 5: Cell Banking, 6: Expression of Cloned Proteins in Mammalian Cells: Regulation of Cell-Associated Parameters, 7: Assay Requirements for Cell Culture Process Development, 8: Nonperfused Attachment Systems for Cell Cultivation, 9: Perfusion Systems for Cell Cultivation, 10: Suspension Culture of Mammalian Cells, 11: Microcarrier Culture Systems, 12: Microencapsulation of Mammalian Cells, 13: Continuous Culture with Macroporous Matrix, Fluidized Bed Systems, 14: Downstream Processing of Proteins from Mammalian Cells, 15: Management of Process Technology, 16: Monitoring and Control of Animal Cell Bioreactors: Biochemical Engineering Considerations, 17: Methods for the Detection of Adventitious Viruses in Cell Cultures Used in the Production of Biotechnology Products, 18: Continuous Cell Substrate Considerations, 19: Process Validation for Cell Culture-Derived Pharmaceutical Proteins, 20: Quality Control of rDNA-Derived Human Tissue-Type Plasminogen Activator, 21: Design and Construction of Manufacturing Facilities for Mammalian Cell-Derived Pharmaceuticals, 22: Large-Scale Propagation of Insect Cells, Index

Editorial Reviews

An interdisciplinary approach, integrating biochemistry, biology, genetics, and engineering for the effective production of protein pharmaceuticals. The volume offers a biological perspective of large- scale animal cell culture and examines diverse processing strategies, process management, regulatory aspects of cell culture manufacturing, and emerging host systems closely related to mammalian cells. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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