The elucidation of reaction mechanisms generally requires the carefully designed control of molecular symmetry to distinguish between the many possible reaction pathways. Making and Breaking Symmetry in Chemistry emphasises the crucial role played by symmetry in modern synthetic chemistry. After discussion of a number of famous classical experiments, the advances brought about by the introduction of new techniques, in particular NMR spectroscopy, are exemplified in numerous cases taken from the recent literature. Experimental verification of many of the predictions made in Woodward and Hoffmann's explication of the Conservation of Orbital Symmetry are described. Applications that involve the breaking of molecular symmetry to resolve these and other mechanistic problems in organic, inorganic and organometallic chemistry are presented in the first sections of the book, together with many examples of the detection of hitherto hidden rearrangement processes.
Subsequently, under the aegis of making molecular symmetry, examples of the preparation of highly symmetrical molecules found in the organic, organometallic or inorganic domains are discussed. These include Platonic hydrocarbons or boranes, tetrahedranes, cubanes, prismanes, dodecahedrane, fullerene fragments such as corannulene, sumanene or semibuckminsterfullerene, and other systems of unusual geometries or bonding characteristics (Möbius strips, molecular brakes and gears, Chauvin's carbomers, Fitjer's rotanes, persubstituted rings, metal-metal multiple bonds, etc.). The text also contains vignettes of many of the scientists who made these major advances, as well as short sections that briefly summarise key features of important topics that underpin the more descriptive material. These include some aspects of chirality, NMR spectroscopy, and the use of isotopic substitution to break molecular symmetry. A brief appendix on point group symmetry and nomenclature is also helpfully provided.
Contents:
- Preface
- About the Author
- Introduction
- Symmetry Breaking in Classic Mechanistic Investigations
- Experimental Validation of the Conservation of Orbital Symmetry
- Symmetry Breaking in Reaction Mechanisms and Rearrangements: The Spectroscopic, X-ray Crystallographic and Computational Approach
- The Detection and Elucidation of Hidden Molecular Rearrangements
- A Miscellany of Periodic Table Relationships
- Molecules of Very High Symmetry
- Enhancing Rotational Symmetry
- Appendix — A Brief Introduction to Symmetry Point Groups
- Index
Readership: Senior undergraduate and graduate courses on organic/inorganic/organometallic chemistry reaction mechanisms and synthesis, spectroscopy, and crystallography. Researchers in the field.
Dr Michael J McGlinchey is Emeritus Professor at University College Dublin, Ireland where, after spending 30 years at McMaster University in Canada, he became Chair of Inorganic Chemistry (2002–2010), Head of Department (2003–2005), Head of School (2005–2007), and Director of Dublin Chemistry (2008–2010). He is an elected Fellow of the Chemical Institute of Canada (since 1985) and Royal Irish Academy (since 2008). He is a recipient of the Alcan Award in 2000 from the Canadian Society for Chemistry for distinguished contributions to inorganic chemistry. He has published about 300 papers in the areas of organic, organometallic and bio-organometallic synthesis and mechanisms, sterically hindered molecules, NMR fluxionality, and X-ray crystallography. He has held visiting professorships in France (Rennes, Paris, Versailles, Toulouse), Switzerland (Geneva, Lausanne), People's Republic of China (Heilongjiang, Siping) and the National University of Singapore. He holds a PhD from the University of Manchester, UK.
'This is an interesting, non-mathematical treatment of the subject. Prof. McGlinchey has an excellent reputation as a researcher and teacher internationally.' - J J VittalEmeritus Professor, National University of Singapore, Singapore
'This book illustrates how chemical reactivity is controlled by molecular and electronic symmetry. Professor McGlinchey applies symmetry-based arguments to explore the origins of well-known phenomena which illustrate fundamental principles, and then use these examples to thread together the arcana of organic, inorganic and organometallic chemistry. What makes this approach so appealing and effective is that it brings together seemingly disparate subjects, crosses traditional discipline-based boundaries and allows the building of conceptual bridges. Complex arrays of structural patterns and chemical behavior are linked by simple unifying ideas, which lighten the otherwise overwhelming burden of facts that fill most chemistry textbooks. In addition, McGlinchey 'humanizes' his analysis by providing vignettes of the lives of some of the individuals whose discoveries molded the way we think about chemistry. The refreshingly light and catholic nature of its presentation will be an exciting and useful read for all those interested in the way the molecular and electronic structure control chemistry.' - Richard OakleyEmeritus Professor, University of Waterloo, Canada
The elucidation of reaction mechanisms generally requires the carefully designed control of molecular symmetry to distinguish between the many possible reaction pathways. Making and Breaking Symmetry in Chemistry emphasises the crucial role played by symmetry in modern synthetic chemistry. After discussion of a number of famous classical experiments, the advances brought about by the introduction of new techniques, in particular NMR spectroscopy, are exemplified in numerous cases taken from the recent literature. Experimental verification of many of the predictions made in Woodward and Hoffmann's explication of the Conservation of Orbital Symmetry are described. Applications that involve the breaking of molecular symmetry to resolve these and other mechanistic problems in organic, inorganic and organometallic chemistry are presented in the first sections of the book, together with many examples of the detection of hitherto hidden rearrangement processes.
Subsequently, under the aegis of making molecular symmetry, examples of the preparation of highly symmetrical molecules found in the organic, organometallic or inorganic domains are discussed. These include Platonic hydrocarbons or boranes, tetrahedranes, cubanes, prismanes, dodecahedrane, fullerene fragments such as corannulene, sumanene or semibuckminsterfullerene, and other systems of unusual geometries or bonding characteristics (Möbius strips, molecular brakes and gears, Chauvin's carbomers, Fitjer's rotanes, persubstituted rings, metal-metal multiple bonds, etc.). The text also contains vignettes of many of the scientists who made these major advances, as well as short sections that briefly summarise key features of important topics that underpin the more descriptive material. These include some aspects of chirality, NMR spectroscopy, and the use of isotopic substitution to break molecular symmetry. A brief appendix on point group symmetry and nomenclature is also helpfully provided.
Contents:
- Preface
- About the Author
- Introduction
- Symmetry Breaking in Classic Mechanistic Investigations
- Experimental Validation of the Conservation of Orbital Symmetry
- Symmetry Breaking in Reaction Mechanisms and Rearrangements: The Spectroscopic, X-ray Crystallographic and Computational Approach
- The Detection and Elucidation of Hidden Molecular Rearrangements
- A Miscellany of Periodic Table Relationships
- Molecules of Very High Symmetry
- Enhancing Rotational Symmetry
- Appendix — A Brief Introduction to Symmetry Point Groups
- Index
Readership: Senior undergraduate and graduate courses on organic/inorganic/organometallic chemistry reaction mechanisms and synthesis, spectroscopy, and crystallography. Researchers in the field.
Dr Michael J McGlinchey is Emeritus Professor at University College Dublin, Ireland where, after spending 30 years at McMaster University in Canada, he became Chair of Inorganic Chemistry (2002–2010), Head of Department (2003–2005), Head of School (2005–2007), and Director of Dublin Chemistry (2008–2010). He is an elected Fellow of the Chemical Institute of Canada (since 1985) and Royal Irish Academy (since 2008). He is a recipient of the Alcan Award in 2000 from the Canadian Society for Chemistry for distinguished contributions to inorganic chemistry. He has published about 300 papers in the areas of organic, organometallic and bio-organometallic synthesis and mechanisms, sterically hindered molecules, NMR fluxionality, and X-ray crystallography. He has held visiting professorships in France (Rennes, Paris, Versailles, Toulouse), Switzerland (Geneva, Lausanne), People's Republic of China (Heilongjiang, Siping) and the National University of Singapore. He holds a PhD from the University of Manchester, UK.
'This is an interesting, non-mathematical treatment of the subject. Prof. McGlinchey has an excellent reputation as a researcher and teacher internationally.' - J J VittalEmeritus Professor, National University of Singapore, Singapore
'This book illustrates how chemical reactivity is controlled by molecular and electronic symmetry. Professor McGlinchey applies symmetry-based arguments to explore the origins of well-known phenomena which illustrate fundamental principles, and then use these examples to thread together the arcana of organic, inorganic and organometallic chemistry. What makes this approach so appealing and effective is that it brings together seemingly disparate subjects, crosses traditional discipline-based boundaries and allows the building of conceptual bridges. Complex arrays of structural patterns and chemical behavior are linked by simple unifying ideas, which lighten the otherwise overwhelming burden of facts that fill most chemistry textbooks. In addition, McGlinchey 'humanizes' his analysis by providing vignettes of the lives of some of the individuals whose discoveries molded the way we think about chemistry. The refreshingly light and catholic nature of its presentation will be an exciting and useful read for all those interested in the way the molecular and electronic structure control chemistry.' - Richard OakleyEmeritus Professor, University of Waterloo, Canada
MAKING AND BREAKING SYMMETRY IN CHEMISTRY: Syntheses, Mechanisms and Molecular Rearrangements
292
MAKING AND BREAKING SYMMETRY IN CHEMISTRY: Syntheses, Mechanisms and Molecular Rearrangements
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Product Details
| ISBN-13: | 9789811249679 |
|---|---|
| Publisher: | WSPC |
| Publication date: | 03/09/2022 |
| Sold by: | Barnes & Noble |
| Format: | eBook |
| Pages: | 292 |
| File size: | 14 MB |
| Note: | This product may take a few minutes to download. |