Table of Contents
1. The Evolving Concept of Schizophrenia
2. Candidate Neuronal Circuits
3. When Does Schizophrenia Begin?
4. Clues from Drugs Which Affect Dopamine, Glutamate, and Other Neurotransmitters
5. Clues from Psychophysiology
6. Neuropsychological Studies
7. Imaging Brain Structure in Living Patients
8. Imaging Brain Function in Living Patients
9. Imaging Brain Chemistry and the Question of Neuronal Degeneration
10. Likely Components of the Final Common Pathway
11. Early Models of the Final Common Pathway 1. Disconnection and Coordination
12. Early Models of the Final Common Pathway 2. Basal Ganglia-Thalamocortical Circuits
13. Do the Models Fit With What We Know About Schizophrenia?
14. Implications for Treatment
15. The Way Forward