Neural Crest and Placodes
Neural Crest and Placodes provides in-depth coverage of the topic, including information on their critical role in vertebrate development, evolution, and the way defects in their development underlie a wide range of congenital disorders. It delves deep into advances made in our understanding of the mechanisms governing the formation, migration, and differentiation of these two cell populations, also discussing their integration during embryonic development. The text highlights the application of fundamental knowledge in investigating the etiology and pathogenesis of congenital disorders and the ways the data applies to the field of regenerative medicine. - Written by leading experts in the field - Includes descriptions of the most recent advances in the field - Highlights the applications of this knowledge in investigating the etiology and pathogenesis of congenital disorders - Explores their usage in the field of regenerative medicine
1141903526
Neural Crest and Placodes
Neural Crest and Placodes provides in-depth coverage of the topic, including information on their critical role in vertebrate development, evolution, and the way defects in their development underlie a wide range of congenital disorders. It delves deep into advances made in our understanding of the mechanisms governing the formation, migration, and differentiation of these two cell populations, also discussing their integration during embryonic development. The text highlights the application of fundamental knowledge in investigating the etiology and pathogenesis of congenital disorders and the ways the data applies to the field of regenerative medicine. - Written by leading experts in the field - Includes descriptions of the most recent advances in the field - Highlights the applications of this knowledge in investigating the etiology and pathogenesis of congenital disorders - Explores their usage in the field of regenerative medicine
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Neural Crest and Placodes

Neural Crest and Placodes

Neural Crest and Placodes

Neural Crest and Placodes

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Overview

Neural Crest and Placodes provides in-depth coverage of the topic, including information on their critical role in vertebrate development, evolution, and the way defects in their development underlie a wide range of congenital disorders. It delves deep into advances made in our understanding of the mechanisms governing the formation, migration, and differentiation of these two cell populations, also discussing their integration during embryonic development. The text highlights the application of fundamental knowledge in investigating the etiology and pathogenesis of congenital disorders and the ways the data applies to the field of regenerative medicine. - Written by leading experts in the field - Includes descriptions of the most recent advances in the field - Highlights the applications of this knowledge in investigating the etiology and pathogenesis of congenital disorders - Explores their usage in the field of regenerative medicine

Product Details

ISBN-13: 9780124078901
Publisher: Elsevier Science & Technology Books
Publication date: 02/03/2015
Series: Current Topics in Developmental Biology , #111
Sold by: Barnes & Noble
Format: eBook
Pages: 542
File size: 16 MB
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About the Author

Paul Trainor, PhD is an Investigator at the Stowers Institute for Medical Research in Kansas City, MO USA with over 20 years of experience working in the fields of developmental biology, neurobiology and craniofacial morphogenesis. He received his PhD from the University of Sydney, Australia under the tutelage of Dr Patrick Tam before undertaking post-doctoral training with Dr Robb Krumlauf at the National Institute for Medical Research in London, England. The current emphasis of Dr Trainor’s research centres on the role of neural crest cells in craniofacial evolution, development and disease. He seeks to understand the mechanisms that regulate neural crest cell patterning and apply this basic knowledge to decipher the etiology and pathogenesis of birth defects and potentially develop therapeutic avenues for their prevention. His laboratory studies neurocristopathies (disorders of neural crest cell development) such as Treacher Collins syndrome, Holoprosencephaly and Syngnathia as well as other neurocristopathy disorders such as Hirschsprung disease. Dr Trainor is currently vice-present of the Society for Craniofacial Genetics and Development.

Table of Contents

Neural Crest Cells1. Neural Crest Cell Evolution: How and when did a Neural Crest Cell become a Neural Crest CellWilliam A Muñoz and Paul A Trainor2. Resolving Time and Space Constraints during Neural Crest Formation and DelaminationJean-Loup Duband, Alwyn Dady and Vincent Fleury3. Extended Multipotency of Neural Crest Cells and Neural Crest-Derived CellsTsutomu Motohashi and Takahiro Kunisada4. The Ciliary Baton: Orchestrating Neural Crest Cell DevelopmentChing-Fang Chang, Elizabeth N. Schock, Aria Attia, Rolf W. Stottmann and Samantha A. Brugmann5. Receptor Tyrosine Kinase Signaling: Regulating Neural Crest Development One Phosphate at a TimeKatherine A. Fantauzzo and Philippe Soriano6. Neural Crest Cells in Cardiovascular DevelopmentAlice Plein, Alessandro Fantin and Christiana Ruhrberg7. Molecular Control of the Neural Crest and Peripheral Nervous System DevelopmentJason M. Newbern Placodes8. Vertebrate Cranial Placodes as Evolutionary Innovations – The Ancestor's TaleGerhard Schlosser9. Transcriptional Regulation of Cranial Sensory Placode DevelopmentSally A. Moody and Anthony-Samuel LaMantia10. Neural Crest and Placode Contributions to Olfactory DevelopmentJun Suzuki and Noriko Osumi11. Epithelial Morphogenesis: The Mouse Eye as a Model SystemBharesh Chauhan, Timothy Plageman and Richard Lang12. Developing and Regenerating a Sense of TasteLinda A. Barlow  and Ophir D. Klein13. Signaling in Tooth, Hair and Mammary PlacodesYoungwook Ahn14. The Role of Foxi Family Transcription Factors in the Development of the Ear and JawRenée K. Edlund, Onur Birol and Andrew K. Groves15. The Use of Human Pluripotent Stem Cells for the in Vitro Derivation of Cranial Placodes and Neural Crest CellsBianca E Borchin and Tiziano Barberi

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This text explores the advances made in our understanding of the mechanisms governing the formation, migration, and differentiation of neural crest and placodel populations and their integration during embryonic development.

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