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Overview

Grooming is among the most evolutionary ancient and highly represented behaviours in many animal species. It represents a significant proportion of an animal's total activity and between 30-50% of their waking hours. Recent research has demonstrated that grooming is regulated by specific brain circuits and is sensitive to stress, as well as to pharmacologic compounds and genetic manipulation, making it ideal for modelling affective disorders that arise as a function of stressful environments, such as stress and post-traumatic stress disorder. Over a series of 12 chapters that introduce and explicate the field of grooming research and its significance for the human and animal brain, this book covers the breadth of grooming animal models while simultaneously providing sufficient depth in introducing the concepts and translational approaches to grooming research. Written primarily for graduates and researchers within the neuroscientific community.

Product Details

ISBN-13: 9780511849916
Publisher: Cambridge University Press
Publication date: 05/20/2010
Sold by: Barnes & Noble
Format: eBook
File size: 2 MB

About the Author

Allan V. Kalueff is professor of neuroscience in the Department of Physiology and Biophysics at Georgetown University Medical School. He publishes actively on models of drug-drug and drug-receptor interactions, theories of brain disorders and their therapy, and complex interplay between cognitive, motivational and genetic bases of animal behavior.
Carisa L. Bergner is a researcher in the Department of Physiology and Biophysics at Georgetown University Medical School. Her research currently involves mouse and zebrafish models of stress and depression.
Justin L. La Porte holds a position at the National Institute of Mental Health in Bethesda, Maryland, USA. His research employs behavioral pharmacology and molecular genetics approaches to elucidate the pathogenetic mechanisms of psychiatric disorders such as depression, anxiety, and obsessive-compulsive disorder, with a specific focus on the role of serotonin transporter.

Table of Contents

Preface; 1. Grooming, sequencing, and beyond: how it all began M. Frances Stilwell and John C. Fentress; 2. Self-grooming as a form of olfactory communication in meadow voles and prairie voles (Microtus spp.) Michael H. Ferkin and Stuart T. Leonard; 3. Phenotyping and genetics of rodent grooming and barbering: utility for experimental neuroscience research Carisa L. Bergner, Amanda N. Smolinsky, Brett D. Dufour, Justin L. LaPorte, Peter C. Hart, Rupert J. Egan and Allan V. Kalueff; 4. Social play, social grooming and the regulation of social relationships Sergio M. Pellis and Vivien C. Pellis; 5. Grooming syntax as a sensitive measure of the effects of subchronic PCP treatment in rats Marie-Claude Audet and Sonia Goulet; 6. Modulatory effects of estrogens on grooming and related behaviours Rachel A. Hill and Wah Chin Boon; 7. Lack of barbering behaviour in the phospholipase Cβ1 mutant mice, a model animal for schizophrenia Hee-Sup Shin, Daesoo Kim and Hae-Young Koh; 8. Grooming after cerebellar, basal ganglia, and neocortical lesions R. Lalonde and C. Strazielle; 9. Striatal implementation of action sequences and more: grooming chains, inhibitory gating and relative reward effect Howard Casey Cromwell; 10. An ethological analysis of barbering behaviour Brett D. Dufour and Joseph P. Garner; 11. Should there be a category: 'grooming disorders'? Lara J. Hoppe, Jonathan Ipser, Christine Lochner, Kevin G. F. Thomas and Dan J. Stein; 12. Neurobiology of trichotillomania Srinivas Singisetti, Sam R. Chamberlain and Naomi A. Fineberg; Index.
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