Oxygen Transport in Red Blood Cells: Proceedings of the 12th Aharon Katzir Katchalsky Conference, Tours, France, 4-7 April 1984

by Claude Nicolau (Editor)

Overview

Oxygen Transport in Red Blood Cells contains the proceedings of the 12th Aharon Katzir Katchalsky Conference held at Tours, France on April 4-7, 1984. Organized into 16 chapters, this book begins with a discussion on the influence of heme pocket geometry on ligand binding to heme proteins. Subsequent chapters describe a genetic approach to producing oxygen affinity differences; clinical importance of the oxygen transport function of preserved red blood cells; methods for the measurement of oxygen equilibrium curves of red cell suspensions and hemoglobin solutions; and aspects of oxygen supply to tissue. Other chapters elucidate interactions between hemoglobin and erythrocyte membrane and membrane protein oxidation; incorporation of allosteric effectors of hemoglobin in red blood cells; and significance of low hemoglobin oxygen affinity.The interaction of ligands and other molecules with hemoglobin and the storage of red blood cells having incorporated exogenous allosteric effectors of hemoglobin are also explained.

Product Details

ISBN-13:	9781483160443
Publisher:	Pergamon
Publication date:	10/22/2013
Sold by:	Barnes & Noble
Format:	eBook
Pages:	204
File size:	7 MB

Table of Contents

List of ContributorsInfluence of Heme Pocket Geometry on Ligand Binding to Heme ProteinsA Genetic Approach to Producing Oxygen Affinity DifferencesOxygen-Bioenergetics and 31P NMR In VivoClinical Importance of the Oxygen Transport Function of Preserved Red Blood CellsMethods for the Measurement of Oxygen Equilibrium Curves of Red Cell Suspensions and Hemoglobin SolutionsAspects of Oxygen Supply to TissueInteractions between Hemoglobin and Erythrocyte Membrane and Membrane Protein OxidationInteractions between O2 and 002 in the BloodOxygen Supply to the BrainOxygen Supply to the Brain under Hypoxie and Hyperoxic ConditionsNuclear Medicine Investigations of the Oxygen Dependent Metabolism of the Heart MuscleIncorporation of Allosteric Effectors of Hemoglobin in Red Blood Cells. Biochemical and Physiological EffectsFlow Compensation with Oxygen Equilibrium Curve ShiftsSignificance of Low Hemoglobin Oxygen AffinityHemoglobin Solutions as Oxygen Carriers: Ligands and Other Molecules Interacting with HemoglobinStorage of Red Blood Cells Having Incorporated Exogenous Allosteric Effectors of HemoglobinIndex