Principles of Hormone/Behavior Relations

by Donald W. Pfaff, Robert T Rubin, Jill E. Schneider, Geoff Head

Overview

Principles of Hormone/Behavior Relations, Second Edition, provides an introduction to the underlying principles of endocrine regulation of behavior, a newly emerging area of research within neurobiology and endocrinology. It addresses the properties of hormone/behavior relations, including the influence of family background, timing issues, neuroanatomical features, cellular mechanisms, and the importance of environmental context and evolution. This new edition incorporates critical advances in the field, also including increased coverage of hormonal influences on food intake, and on the cardiovascular system. The addition of entirely new principles provides further coverage of epigenetics and appetite. Thoroughly revised and updated, this book is an ideal resource for neuroscientists and researchers engaging in this rapidly expanding field of study. - Provides a unique structure where each chapter addresses a key principle that is illustrated by numerous basic experimental and clinical examples - Includes user-friendly features, such as boxed figures with extended captions and references, numerous clinical notes, and a comprehensive list of abbreviations - Contains numerous illustrations that highlight both the clinical and basic science information

Product Details

ISBN-13:	9780128026670
Publisher:	Elsevier Science & Technology Books
Publication date:	01/10/2018
Sold by:	Barnes & Noble
Format:	eBook
Pages:	572
File size:	62 MB
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About the Author

Donald W. Pfaff heads the Laboratory of Neurobiology and Behavior at The Rockefeller University. He received his scientific training at Harvard College and MIT. He is a Member of the U.S. National Academy of Sciences and a Fellow of the American Academy of Arts and Sciences. Pfaff's laboratory focuses on steroid hormones and brain function, genes influencing neuronal functions, and generalized CNS arousal. He is the author or coauthor of over 10 books and more than 900 research publications.VA Greater Los Angeles Healthcare System, Los Angeles, CA, USAProfessor Jill E. Schneider has been teaching undergraduate courses in Behavioral Endocrinology and other topics in neuroscience at Lehigh University for over 25 years. She received graduate and postdoctoral training in biology and neuroscience at Wesleyan University and the University of Massachusetts, respectively, and was awarded the Frank A. Beach Award from the Society for Behavioral Neuroendocrinology for outstanding research in behavioral neuroendocrinology in 1991. Professor Schneider's National Science Foundation-funded neuroendocrinology laboratory is focused on metabolic and hormonal mechanisms at the interface of reproductive and ingestive behavior.
Professor Jill E. Schneider has been teaching undergraduate courses in Behavioral Endocrinology and other topics in neuroscience at Lehigh University for over 25 years. She received graduate and postdoctoral training in biology and neuroscience at Wesleyan University and the University of Massachusetts, respectively, and was awarded the Frank A. Beach Award from the Society for Behavioral Neuroendocrinology for outstanding research in behavioral neuroendocrinology in 1991. Professor Schneider’s National Science Foundation-funded neuroendocrinology laboratory is focused on metabolic and hormonal mechanisms at the interface of reproductive and ingestive behavior.

Read an Excerpt

Provides a broad overview of the effects of hormones on behavior in man and animals.

Table of Contents

Section I: Characterizing the Phenomena: Hormone Effects are Strong and Reliable1. Hormones Can Both Facilitate and Repress Behavioral Responses2. One Hormone Can have Many Effects: A Single Hormone Can Affect Complex Behaviors3. Hormone Combinations Can be Important for Influencing an Individual Behavior4. Hormone Metabolites Can be the Behaviorally Active Compounds5. There are Optimal Hormone Concentrations: Too Much or Too Little Can be Damaging6. Hormones Do Not ''Cause'' Behavior; They Alter Probabilities of Responses to Given Stimuli Section II: History: Hormone Effects Can Depend on Family, Gender, and Development7. Familial/Genetic Dispositions to Hormone Responsiveness Can Influence Behavior8. The Sex of the Recipient can Influence the Behavioral Response9. Hormone Actions Early in Development Can Influence Hormone Responsiveness in the CNS During Adulthood10. Puberty Alters Hormone Secretion and Hormone Responsivity and Heralds Sex Differences11. Changes in Hormone Levels and Responsiveness During Aging Affect Behavior Section III: Time: Hormonal Effects on Behavior Depend on Temporal Parameters12. Duration of Hormone Exposure Can Make a Big Difference: In Some Cases Longer is Better; In Other Cases Brief Pulses are Optimal for Behavioral Effects13. Hormonal Secretions and Responses are Affected by Biological Clocks Section IV: Space: Spatial Aspects of Hormone Administration and Impact are Important14. Effects of a Given Hormone Can be Widespread Across the Body; Central Effects Consonant with Peripheral Effects Form Coordinated, Unified Mechanisms15. Hormones Can Act at All Levels of the Neuraxis to Exert Behavioral Effects; The Nature of the Behavioral Effect Depends on the Site of Action Section V: Mechanisms: Molecular and Biophysical Mechanisms of Hormone Actions Give Clues to Future Therapeutic Strategies16. In Responsive Neurons, Rapid hormone Effects Can Facilitate Later Genomic Actions17. Gene Duplication and Splicing Products for Hormone Receptors in the CNS Often Have Different Behavioral Effects18. Hormone Receptors and Other Nuclear Proteins Influence Hormone Responsiveness Section VI: Environment: Environmental Variables Influence Hormone/Behavior Relations19. Hormone Effects on Behavior Depend Upon Context20. Behavioral/Environmental Context also Alters Hormone Release Section VII: Evolution21. Neuroendocrine Mechanisms Have Been Conserved to Provide Biologically Adaptive Body/Brain/Behavior Coordination

What People are Saying About This

From the Publisher

Provides a broad overview of the effects of hormones on behavior in man and animals.

Editorial Reviews

"The text is a pleasure to read. The authors adopt an informal conversational style for their discussion that evokes the comfortable air of a seminar course with a favorite professor. ...It invites and excites the reader to dig deeper into the many uncertain and unexplained areas of neuroendocrinology. It shows the reader that this is a field ready for exciting advances and a worthy arena in which to spend one’s career." —William J. Kovacs, The University of Texas Southwestern Medical Center, Dallas in BRAIN, BEHAVIOR AND IMMUNITY (July 2005) "This is an exceptional text that provides an up-to-date and comprehensive review of topical material in endocrinology, neuroscience, and behavior...The emphasize on research approaches, balanced with integration of findings from such approaches, enables the text to be used by a broad range of student populations. It would be suitable for use in an advanced undergraduate class, as well as by graduate and medial students, alike.” —Cheryl Frye, University of Albany

From the Publisher