Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine.
Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development.
The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences.
- Provides an overview of the growing field of precision medicine
- Contains chapters from geographically diverse experts in their field
- Explores important aspects of precision medicine, including applications, ethics, and development
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About the Author
Dr. Mukesh Verma is a Program Director and Chief in the Methods and Technologies Branch (MTB), Epidemiology and Genetics Research Program (EGRP) of the Division of Cancer Control and Population Sciences (DCCPS) at the National Cancer Institute (NCI), National Institutes of Health (NIH). Before coming to the DCCPS, he was a Program Director in the Division of Cancer Prevention (DCP), NCI, providing direction in the areas of biomarkers, early detection, risk assessment and prevention of cancer, epigenetics, epidemiology, and cancers associated with infectious agents. Since joining the NCI, he has sought to champion the visibility of and investment in cancer epigenetics research both within the Institute and across other federal and non-governmental agencies, and to raise public awareness about controlling cancer. He represents NIH in Common Fund Programs on Epigenomics, Metabolomics, and Molecular Transducers of Physical Activity. Dr. Mukesh Verma holds a M.Sc. from Pantnagar University and a Ph.D. from Banaras Hindu University. He did postdoctoral research at George Washington University and was a faculty member at Georgetown University Medical Center. He has published 161 research articles and reviews and edited five books in cancer biomarkers, epigenetics and epidemiology field.M.Sc. (Applied Genetics), M.Tech. (Biotechnology), M.Phil. (Biotechnology), Ph.D. (Biotechnology), Ph.D. (Bioinformatics), Post-Doc (Bioinformatics), PGDM, is honorary Principal Scientist at Institute of Integrative Omics and Applied Biotechnology (IIOAB), India- a virtual global platform of multidicipliary research and advocacy. He is blended with both academic and industrial research and has more than 12 yrs bioinformatics and personalized diagnostic/ medicine Industry experience where his main focus is to translate academic research into high value commercial products for common mans’ reach. He has published more than 150 articles in reputed international journals and has edited 15 cutting-edge omics related reference books published by Taylor& Francis, Springer, Elsevier etc. He has also co-authored 30+ book chapters. Dr. Barh also frequently reviewes articles for Nature publications, Elsevier, BMC Series, PLoS One etc like international Journals. Due to his significant contribution in the field; he has been recognized by Who's Who in the World and Limca Book of Records.
Table of Contents
1. Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment 2. Clinical Next-Generation Sequencing: Enabling Precision Medicine 3. Phenotyping in Precision Medicine 4. Cancer Genetic Screening and Ethical Considerations for Precision Medicine 5. Precision Medicine in Primary Health Care 6. Population Approach to Precision Medicine 7. Regulation of Genomic Testing in the Era of Precision Medicine 8. Image-Based Modeling and Precision Medicine 9. Sharing Outside the Sandbox? The Child’s Right to an Open Data Sharing Future in Genomics and Personalized Medicine 10. Lessons Learned From Cohort Studies, and Hospital-Based Studies and Their Implications in Precision Medicine 11. Clinical Trials in Precision Medicine 12. Time to Educate Physicians and Hospital Staff in Electronic Medical Records for Precision Medicine 13. Computational Approaches in Precision Medicine 14. Handling Big Data in Precision Medicine 15. Trends in Precision Medicine 16. Personalized Medicine: Interdisciplinary Perspective, World Tidal Wave, and Potential Growth for the Emerging Countries