Quality Control and Evaluation of Herbal Drugs: Evaluating Natural Products and Traditional Medicine

by Pulok K. Mukherjee

Overview

Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs' activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. - Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes - Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis - Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine - Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues - References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

Product Details

ISBN-13:	9780128133989
Publisher:	Elsevier Science
Publication date:	05/30/2019
Sold by:	Barnes & Noble
Format:	eBook
Pages:	784
File size:	98 MB
Note:	This product may take a few minutes to download.

About the Author

Prof. Pulok Kumar Mukherjee is working as the Director, Institute of Bioresources and Sustainable Development, under Department Biotechnology, Govt. of India, at Imphal, Manipur. He worked as the Director of the School of Natural Product Studies and Professor (On lien), Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has made several innovative and outstanding contributions in academic/research on development of Bio-economy from Bioresources particularly on traditional medicine inspired drug discovery from Indian medicinal plants, Ethno pharmacology and evidence based validation of herbs used in medicine and food to make them available from 'Farm to Pharma'. Prof. Mukherjee is a Fellow of the Royal Society of Chemistry (FRSC), West Bengal Academy of Sciences (FAScT), National Academy of Agricultural Sciences, India (FNAAS), and the National Academy of Sciences, India (FNASc). He has contributed over 230 publications in peer-reviewed impact journals, several patents, and books on evaluation of botanicals. His works on translational research on traditional medicine are useful bio-prospecting tools for the development of drugs from nature and ancestors. For further details please visit www.pulokmukherjee.in
Prof. Pulok Kumar Mukherjee is working as the Director, Institute of Bioresources and Sustainable Development, under Department Biotechnology, Govt. of India, at Imphal, Manipur. He worked as the Director of the School of Natural Product Studies and Professor (On lien), Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has made several innovative and outstanding contributions in academic/research on development of Bio-economy from Bioresources particularly on traditional medicine inspired drug discovery from Indian medicinal plants, Ethno pharmacology and evidence based validation of herbs used in medicine and food to make them available from ‘Farm to Pharma’. Prof. Mukherjee is a Fellow of the Royal Society of Chemistry (FRSC), West Bengal Academy of Sciences (FAScT), National Academy of Agricultural Sciences, India (FNAAS), and the National Academy of Sciences, India (FNASc). He has contributed over 230 publications in peer-reviewed impact journals, several patents, and books on evaluation of botanicals. His works on translational research on traditional medicine are useful bio-prospecting tools for the development of drugs from nature and ancestors. For further details please visit www.pulokmukherjee.in

Table of Contents

1. Traditional systems of medicines and harmonization2. Ethnopharmacology and ethnomedicines-inspired drug development3. Quality evaluation of herbal medicines: Challenges and opportunities4. Qualitative analysis for evaluation of herbal drugs5. Morphological and microscopical evaluations6. Extraction and other downstream procedures for evaluation of herbal drugs7. Bioactive phyto-components and their analysis8. Thin layer chromatography for evaluation of herbal drugs9. High performance thin layer chromatography (HPTLC) for analysis of herbal drugs10. High performance liquid chromatography for analysis of herbal drugs11. LC-MS: A rapid technique for understanding the plant metabolomic analysis12. Chemo-profiling and marker analysis for quality evaluation of herbal drugs13. Bioassay guided isolation and evaluation of herbal drugs14. Enzyme inhibition studies for evaluation of herbal drugs15. Evaluation of herbal drugs for antimicrobial and parasiticidal effects16. Antiviral evaluation of herbal drugs17. Plant metabolomics and quality evaluation of herbal drugs18. Safety related quality issues for development of herbal drugs19. Quality assurance of herbal drugs and stability testing20. Phytopharmaceuitcals, nutraceuticals and their evaluation21. Regulatory harmonization and good quality practices for development of herbal medicine

What People are Saying About This

From the Publisher

A comprehensive guide to the analytical methods, techniques and approaches for evaluating purity, quality, safety and efficacy of herbal drugs