Side Effects: A Prosecutor, a Whistleblower, and a Bestselling Antidepressant on Trial

Side Effects: A Prosecutor, a Whistleblower, and a Bestselling Antidepressant on Trial

by Alison Bass
Side Effects: A Prosecutor, a Whistleblower, and a Bestselling Antidepressant on Trial

Side Effects: A Prosecutor, a Whistleblower, and a Bestselling Antidepressant on Trial

by Alison Bass

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Overview

As the mental health reporter for the Boston Globe, Alison Bass's front-page reporting on conflicts of interest in medical research stunned readers, and her series on sexual misconduct among psychiatrists earned a Pulitzer Prize nomination. Now she turns her investigative skills to a controversial case that exposed the increased suicide rates among adolescents taking antidepressants such as Paxil, Prozac, and Zoloft.

Side Effects tells the tale of a gutsy assistant attorney general who, along with an unlikely whistle-blower at an Ivy League university, uncovered evidence of deception behind one of the most successful drug campaigns in history. Paxil was the world's bestselling antidepressant in 2002. Pediatric prescriptions soared, even though there was no proof that the drug performed any better than sugar pills in treating children and adolescents, and the real risks the drugs posed were withheld from the public. The New York State Attorney General's office brought an unprecedented lawsuit against giant manufacturer GlaxoSmithKline, the maker of Paxil, for consumer fraud. The successful suit launched a tidal wave of protest that changed the way drugs are tested, sold, and marketed in this country.

With meticulous research, Alison Bass shows us the underbelly of the pharmaceutical industry. She lays bare the unhealthy ties between the medical establishment, big pharma, and the FDA—relationships that place vulnerable children and adults at risk every day.

Product Details

ISBN-13: 9781565126435
Publisher: Algonquin Books of Chapel Hill
Publication date: 06/17/2008
Sold by: Hachette Digital, Inc.
Format: eBook
Pages: 260
File size: 2 MB

About the Author

Alison Bass has covered medicine, science, and technology for the Boston Globe and other publications, including the Miami Herald, Psychology Today, and Technology Review. She has received top media awards from the National Mental Health Association and the National Alliance for the Mentally Ill, and an Associated Press First Place Award. She has taught journalism courses at Boston and Brandeis universities and lives in Newton, Massachusetts.

Table of Contents


Author's Note     vii
Prologue: 2004     1
Martin Teicher and the Wonder Drugs, 1988-89     7
Rose Firestein v. New York City, 1989     15
Donna Howard's Quest to Help Her Adopted Daughter, 1990     23
The Empire Strikes Back, September 1991     29
Rose Firestein's Big Gamble: Suing the Pharmaceutical Industry, June 2004     47
The Brown Connection, 1995     57
Donna Howard Talks to the Press and Becomes a Pariah, January 1996     73
The Humiliation of Martin Teicher, October 1996     79
Eliot Spitzer's Crusaders Win Round One against GlaxoSmithKline but Get Knocked Off Course in Round Two, July 2004     91
A Tale of Two Psychiatrists Named Martin, Spring 1998     103
Tonya Brooks Becomes a Nomad, and Rose Firestein Fights to Protect Florida's Foster Children, 2000-2001     117
Donna Howard Discovers That in the Nonprofit World of Patient Advocacy, Money Shouts, Fall 2002     125
Rose Firestein Begins Probing the Paxil Puzzle, Summer 2003     137
Rose Firestein's Epiphany, Winter 2004     153
How Rose Firestein Found the Smoking Gun Memo and Converted the Skeptics, Spring 2004     165
The New York AG v. GlaxoSmithKline, June 2004     179
Wherein Rose Firestein Goes to Court and Annoys aFederal Judge, July 2004     187
GlaxoSmithKline Comes to the Table, August 2004     197
Martin Teicher Is Vindicated, and Rose Firestein Takes a Bow, Fall 2004     207
Epilogue: Rose Firestein Gets Run Over and Survives, and Donna Howard Turns Out to Have Been Right All Along     221
Acknowledgments     237
Notes     239
Index     253

What People are Saying About This

From the Publisher

"Side Effects is a serious indictment of the pharmaceutical industry, clinical researchers, and government regulators, told in captivating prose. It makes you worry about the authenticity of the evidence that doctors use from day to day." — Dr. Jerome Kassirer, Distinguished Professor at Tufts University School of Medicine, former Editor-in-Chief of New England Journal of Medicine, and author of On the Take: How Medicine's Complicity with Big Business Can Endanger Your Health

"A richly detailed account of the disgraceful self-serving ties between drug companies and the psychiatric profession, as told through stories about the heroes, villains and victims in this drama. An engrossing read and a valuable contribution to public understanding of the need for reform."—Arnold S. Relman, M.D., Professor Emeritus of Medicine and of Social Medicine, Harvard Medical School and Former Editor, New England Journal of Medicine

"This is the riveting story of how one of the world's largest drug companies and a few university researchers on its payroll suppressed evidence that a top-selling antidepressant might actually be dangerous in adolescents. It's also the very human story of how two courageous and persistent women made sure the world learned about it. Reads like a good novel, with lessons that go well beyond this case." — Marcia Angell, M.D., Senior Lecturer in Social Medicine, Harvard Medical School, Former Editor-in-Chief, New England Journal of Medicine

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