Laboratory Animal Anaesthesia

by Paul Flecknell

Overview

Laboratory Animal Anaesthesia, Fourth Edition provides a basic guide to anaesthesia for a very diverse audience needing content, with straight-forward, structured style of writing. Updated with effects of anaesthetics in different laboratory species, including sources of dose rates will be incorporated into tabular material. New information on pain assessment and pain management will be covered, and an increased emphasis on rats and mice for anaesthesia and perioperative care. With newly revised, full color illustrations to facilitate best learning, Laboratory animal Anesthesia, Fourth Edition provides procedures, key points and invaluable advice from a well-known and respected veterinary anesthetist and scientist with over 30 years of experience in the field. - Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area - Focuses on procedures involving rats and mice used in research - Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely, as well as those with more experience to continue a career with laboratory animal model research - Includes rapid, easily accessed information using tabulated summaries

Product Details

ISBN-13:	9780128005781
Publisher:	Elsevier Science & Technology Books
Publication date:	09/21/2015
Sold by:	Barnes & Noble
Format:	eBook
Pages:	350
File size:	8 MB

About the Author

Paul Flecknell is a veterinarian with over 35 years of experience working with laboratory animals. He is a Diplomate of the European Colleges of Veterinary Anaesthesia and Analgesia and Laboratory Animal Medicine and an honorary Diplomate of the American College of Laboratory Animal Medicine. He has PhD in physiology, and is currently Professor of Laboratory Animal Science in the Institute of Neuroscience at Newcastle University. His main research interests are anaesthesia and analgesia of all species of animals and in particular the development of methods of pain assessment. He is the head of the Pain and Animal Welfare Science (PAWS) group at Newcastle. The group's current research work is focussed on novel methods of "cage-side assessment of pain, particularly using "pain faces and developing methods of measurement of affective state in rodents.
Paul Flecknell is a veterinarian with over 35 years of experience working with laboratory animals. He is a Diplomate of the European Colleges of Veterinary Anaesthesia and Analgesia and Laboratory Animal Medicine and an honorary Diplomate of the American College of Laboratory Animal Medicine. He has PhD in physiology, and is currently Professor of Laboratory Animal Science in the Institute of Neuroscience at Newcastle University. His main research interests are anaesthesia and analgesia of all species of animals and in particular the development of methods of pain assessment. He is the head of the Pain and Animal Welfare Science (PAWS) group at Newcastle. The group’s current research work is focussed on novel methods of “cage-side” assessment of pain, particularly using “pain faces” and developing methods of measurement of affective state in rodents.

Table of Contents

Preface vii

Preface to the Second Edition ix

Preface to the First Edition xi

Glossary xiii

List of Tables xv

List of Figures xix

Acknowledgements xxi

Introduction xxiii

1 Preparing for Anaesthesia 1

Anaesthetic equipment and anaesthetic drugs 1

Other equipment 8

Personnel 14

The animal 15

2 Anaesthesia 19

General anaesthesia 20

3 Anaesthetic Management 79

Pre-operative preparations 79

Monitoring anaesthesia 81

Anaesthetic problems and emergencies 95

4 Special Techniques 109

Use of neuromuscular blocking agents 109

Controlled ventilation 113

Long-term anaesthesia 119

Anaesthesia of pregnant animals 131

Anaesthesia of neonates 134

Anaesthesia for imaging 135

5 Analgesia and Post-operative Care 139

The recovery room environment 140

Problems during the recovery period 142

Management of post-operative pain 147

Pain assessment 153

Pain relief 160

Conclusions 179

6 Anaesthesia of Common Laboratory Species: Special Considerations 181

Small rodents 183

Rabbits 204

Cats 212

Dogs 217

Ferrets 221

Pigs 222

Sheep and goats 227

Primates 231

Other species 234

Bibliography 243

Appendix 1 Recommended Techniques and Physiological Data 275

Appendix 2 Estimation of Required Quantities of Volatile Anaesthetics and Anaesthetic Gases 281

Appendix 3 Examples of Dilutions of Anaesthetic Mixtures for Small Rodents 283

Appendix 4 Manufacturers of Equipment and Other Items Illustrated or Cited in the Text 287

Index 291

What People are Saying About This

From the Publisher

A basic guide to anaesthesia for a diverse audience needing straight-forward, structured content

Editorial Reviews

"...a must have for any laboratory animal professional involved with anesthetizing research animals…an affordable essential reference for research personnel, laboratory animal veterinarians, and students." —Journal of the American Veterinary Medical Association

"The preeminent book on laboratory animal anesthesia and analgesia...It is easy to locate information in this one-stop resource on laboratory animal anesthesia...a well organized book that ensures readers are aware of the most important clinical aspects of a topic. Score: 99 - 5 Stars" —Doody's

From the Publisher