Structural and Mechanistic Enzymology

by Tatyana Karabencheva-Christova (Editor)

Overview

Structural and Mechanistic Enzymology, Volume 109, the latest release in the Advances in Protein Chemistry and Structural Biology series, is an essential resource for protein chemists. Chapters in this new volume include Collagenolytic Matrix Metalloproteinase Structure–Function Relationships: Insights from Molecular Dynamics Studies, Computational Glycobiology: Mechanistic Studies of Carbohydrate-Active Enzymes and Implication for Inhibitor Design, Computational Biochemistry─Enzyme Mechanisms Explored, and A Paradigm for C─H Bond Cleavage: Structural and Functional Aspects of Transition State Stabilization by Mandelate Racemase. This series presents new information on protocols and analysis of proteins, with each volume guest edited by leading experts in a broad range of protein-related topics. This volume presents state-of-the-art contributions, providing insights into the relationship between enzyme structure, catalysis, and function. - Provides cutting-edge developments in protein chemistry and structural biology - Features new information about protocols and analysis of proteins - Contains chapters written by authorities in their respective fields - Targeted to a wide audience of researchers, specialists and students

Product Details

ISBN-13:	9780128118771
Publisher:	Elsevier Science & Technology Books
Publication date:	07/17/2017
Series:	Advances in Protein Chemistry and Structural Biology , #109
Sold by:	Barnes & Noble
Format:	eBook
Pages:	366
File size:	54 MB
Note:	This product may take a few minutes to download.

About the Author

Dr. Tatyana Karabencheva-Christova works at the Department of Applied Sciences, University of Northumbria, UK.

Table of Contents

1. Collagenolytic Matrix Metalloproteinase Structure–Function Relationships: Insights from Molecular Dynamics StudiesTatyana G. Karabencheva-Christova, Christo Z. Christov and Gregg B. Fields2. Computational Glycobiology: Mechanistic Studies of Carbohydrate-Active Enzymes and Implication for Inhibitor DesignAndrew P. Montgomery, Kela Xiao, Xingyong Wang, Danielle Skropeta and Haibo Yu3. Computational Biochemistry─Enzyme Mechanisms ExploredMartin Culka, Florian J. Gisdon and G. Matthias Ullmann4. A Paradigm for C─H Bond Cleavage: Structural and Functional Aspects of Transition State Stabilization by Mandelate RacemaseStephen L. Bearne and Martin St. Maurice5. Striking Diversity in Holoenzyme Architecture and Extensive Conformational  Variability in Biotin-Dependent CarboxylasesLiang Tong6. Enzymology of Microbial Dimethylsulfoniopropionate CatabolismMishtu Dey7. Sortase Transpeptidases: Structural Biology and Catalytic MechanismAlex W. Jacobitz, Michele D. Kattke, Jeff Wereszczynski and Robert T. Clubb8. Biology, Mechanism, and Structure of Enzymes in the a-D-Phosphohexomutase SuperfamilyKyle M. Stiers, Andrew G. Muenks and Lesa J. Beamer9.Mechanistic Insights Into Catalytic RNA–Protein Complexes Involved in Translation of the Genetic CodeSatya B. Routh and Rajan Sankaranarayanan

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From the Publisher

Essential resource for protein chemists presents cutting-edge developments in protein chemistry and structural biology