The Benefit/Risk Ratio: A Handbook for the Rational Use of Potentially Hazardous Drugs

by Hans C. Korting, M. Schafer-Korting

Overview

The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio. When prescribing drugs, physicians must look at the big picture of the drug's benefits in relation to its side effects and possib

Product Details

ISBN-13:	9781040204566
Publisher:	CRC Press
Publication date:	07/24/1998
Sold by:	Barnes & Noble
Format:	eBook
Pages:	400
File size:	8 MB

About the Author

Korting, Hans C. | Schafer-Korting, M.

Table of Contents

The Role and Analysis of Benefit and Risk in the Development of New Drugs. Prediction of the Benefit/Risk Ratio from In Vitro Data. Evaluation of Therapeutic Benefits and Toxicological Risks Using Structure-Activity Relational Expert Systems. Improving the Therapeutic Index Through Unusual Routes of Application: Intra-Arterial Treatment of Liver Metastases. Establishing the Benefit/Risk Ration with Combination Drugs. Improving the Therapeutic Index of Antineoplastic Agents through Additional Drugs. Antihypertensive Agents. Diueretics. Anti-Diabetic Drugs. Anticonvulsant Drugs and Drugs for Parkinson's Disease. Antihistamines and Antiserotonins. Cytokines and Immunomodulators. Non-Opioid Analgesics and Anti-Inflammatory Agents. Toxicity Profile of Liposomal Anthacyclines. Antibacterial Agents. Antiviral Agents. Drugs Used in Reproductive Endocrinology. Nicotine Preparations in Smoking. Systemic Drugs for Skin Diseases. Topical Liposome Drugs. Topical Glucocorticoids. Index.

Editorial Reviews

Compiles information which balance a variety of drugs' benefits in relation to side effects and possible toxicities. After introductory chapters concerning methodologies of risk/benefit analysis, chapters provide assessments of drugs such as antihypertensive agents, diuretics, antidiabetics, anticonvulsants, cytokines, immunomodulators, antibacterial and antiviral agents, topical glucocorticoids, liposomal anthracyclines, nonopioid analgesics, systemic drugs for skin diseases, and others. Annotation c. by Book News, Inc., Portland, Or.

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