The Future of Pharmaceutical Product Development and Research

by Rakesh Kumar Tekade PhD (Editor)

Overview

The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals, and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries. - Provides an overview of practical information for clinical trials - Outlines how to ensure an environment that follows Good Manufacturing Practice (GMP) - Examines recent developments and suggests future directions for drug production methods and techniques

Product Details

ISBN-13:	9780128144565
Publisher:	Elsevier Science & Technology Books
Publication date:	08/19/2020
Series:	Advances in Pharmaceutical Product Development and Research
Sold by:	Barnes & Noble
Format:	eBook
Pages:	976
File size:	59 MB
Note:	This product may take a few minutes to download.

About the Author

Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.

Table of Contents

1. Quality by design as an emerging concept in the development of pharmaceuticals Dnyaneshwar Kalyane, Nidhi Raval, Surya Narayana Polaka and Rakesh K. Tekade2. 3D printing as an emerging tool in pharmaceutical product developmentKuldeep Rajpoot, Muktika Tekade, Mukesh Chandra Sharma, SreeHarsha Nagaraja, Basel Arafat and Rakesh K. Tekade3. Artificial intelligence in the pharmaceutical sector: current scene and future prospectDyaneshwar Kalyane, Gaurav Sanap, Debleena Paul, Snehal Shenoy, Neelima Anup, Surya Narayana Polaka, Vishakha Tambe and Rakesh K. Tekade4. Recent advancements in solubilization of hydrophobic drugsKuldeep Rajpoot, Muktika Tekade, SreeHarsha Nagaraja, Mukesh C. Sharma and Rakesh K. Tekade5. Hydrotropy, mixed hydrotropy, and mixed solvency as trending concept for solubilization of lipophilic drugsAnirudh Padiyar, Om Prakash Agrawal, Kuldeep Rajpoot and Rakesh K. Tekade6. Prodrug design for improving the biopharmaceutical properties of therapeutic drugsDevendra Choudhary, Hanmant Goykar, Dnyaneshwar Kalyane, Nagaraja Sreeharsha and Rakesh K. Tekade7. Endosomal escape tendency of drug delivery systems to mediate cytosolic delivery of therapeuticsSandeep Kaur Bansal, Kuldeep Rajpoot, Sreeharsha Nagaraja, Susanne R. Youngren-Ortiz, Neelima Anup and Rakesh K. Tekade8. Mass spectrometry imaging in lipid and proteomic profiling: an emerging tool for cancer diagnosisNagendra Sai Kumar Achanta, A.N.V. Haritha and Rakesh K. Tekade9. Photothermal therapy as emerging combinatorial therapeutic approachChitra Rajani, Vruti Patel, Pooja Borisa, Tukaram Karanwad, Suryanarayana Polaka, Dnyaneshwar Kalyane and Rakesh K. Tekade10. Small interfering RNA-based advanced nanoparticles for the treatment of cancerDevesh Kapoor, Yashu Chourasiya, Anil Pethe, Rahul Maheshwari and Rakesh K. Tekade11. Recent advances in regenerative medicineKuldeep Rajpoot, Maliheh Safavi, Sreeharsha Nagaraja and Rakesh K. Tekade12. Pharmacogenomics and pharmacoepigenomics: Impact on therapeutic strategiesNeetu Soni, Namrata Soni, Rahul Maheshwari, Shreya Thakkar, Dilip Sharma, Rakesh Kumar Tekade, Sreeharsha Nagaraja and Muktika Tekade13. Recombinant blood products and therapeutic enzymes: An updateKuldeep Rajpoot, Muktika Tekade, Mukesh Chandra Sharma, SreeHarsha Nagaraja, Anita Sharma and Rakesh K. Tekade14. New advances in insulin productsKuldeep Rajpoot, Muktika Tekade, Mukesh Chandra Sharma, Nagashekhara Molugulu and Rakesh K. Tekade15. Gene delivery to tackle diabetic nephropathyAkshant Kumawat, Nidhi Raval, Gautham Reddy, Kuldeep Rajpoot and Rakesh K. Tekade16. Resealed erythrocytes (RBCs) and their biomedical applicationKuldeep Rajpoot, Satish Shilpi, Muktika Tekade, Mukesh C. Sharma, Susanne R. Youngren-Ortiz, Pran Kishore Deb, Abhay S. Chauhan and Rakesh K. Tekade17. Proliposomes: a potential colloidal carrier for drug delivery applicationsSatish Shilpi, Devendra Choudhary, Gaurav K. Saraogi, Dhanashree Chordiya, Dnyaneshwar Kalyane and Rakesh K. Tekade18. Gold nanoparticles: An advanced drug delivery and diagnostic toolVikas Pandey, Aditya Ganeshpurkar, Abhilasha Thakur, Megha Sharma, Kuldeep Rajpoot, Muktika Tekade, Sreeharsha Nagaraja and Rakesh K. Tekade19. Advancements in sterile products and admixturesManmohan Singhal, Habban Akhter, Devesh Kapoor, Lakshmi Kanta Kanthal, Yashu Chourasiya, Rahul Maheshwari, Anil Pethe and Rakesh K. Tekade20. Achieving sterility in biomedical and pharmaceutical products (part-I)Anita Sharma, Neelima Anup and Rakesh K. Tekade21. Achieving sterility in biomedical and pharmaceutical products (part-II): radiation sterilizationAnita Sharma, Neelima Anup and Rakesh K. Tekade22. Summary of current regulatory perspective of medical devicesNamdev More, Deepak Ranglani, Govinda Kapusetti and Rakesh K. Tekade23. Clinical trial design for medical devices "emerging pharmaceuticalsB. Divya Latha, Namdev More, Govinda Kapusetti and Rakesh K. Tekade24.

Editorial Reviews

"The book represents a much-needed contribution to the area of pharmaceutical product development and research. It provides a comprehensive (over 900 pages) overview of the trends and perspectives in this area, in an appealing and reader-friendly format." —Doody

From the Publisher