Table of Contents
Section 1: Introduction
- Who are the authors
- Scope of the book
- Handbook of acute management of common poisonings.
- Hands on and practical approach.
- Rationale for drugs included
- How to use the book
- Universal disclaimer
Clinical: Approach to the poisoned patient
- Overview of approach to toxicology/toxinology
- Principles of risk assessment-based approach
- Resuscitation, Risk assessment, Supportive care, Decontamination, Investigations, Enhanced elimination, Antidotes, Disposition
Section 2: Approach to specialist toxicology problems
- Approach to special problems: Approach to snakebite, mushroom poisoning, plant poisoning
- Toxidromes: Serotonin syndrome, Neuroleptic Malignant Syndrome, anticholinergic syndrome, cholinergic syndrome
- Important poisoning manifestations and management: Seizures, coma, hypotension, delirium and agitation
- Drugs of abuse and withdrawal syndromes: Alcohol, amphetamines, opiods, sedative hypnotics, body packers and stuffers
- Investigations: Laboratory results: acidosis, anion gap and osmolar gap, recommended baseline investigations with interpretation. Unit conversion table: ECG interpretation in poisoning: Radiology.
- Special populations: Paediatric poisoning: 1 tablet can kill (list), special precautions in management (overnight stay, paracetamol, risk of charcoal etc); Pregnancy and lactation and poisoning; and Geriatric poisoning
Section 3: Toxic Drugs (78 chapters)
- Approach to diagnosis, investigation and management of the poisoned patient with all of the common drug presentations. Updated with 8 new drug chapters as per readers nominations and feedback
Section 4: Antidotes (29 chapters)
- Detailed description of indications, contraindications, clinical administration and therapeutic end-points for all antidotes. New chapter on Intralipid, the latest development in antidote therapy
Section 5: Toxinology (16 chapters)
- Approach to snakebite, spider and marine envenoming. New chapter on tick envenoming
Section 6: Antivenom (11 chapters)
- Detailed description of indications, contraindications, clinical administration and therapeutic end-points for all antivenoms
Appendices Sample ECGs from poisoned patients; Drug concentrations and unit conversion chart; Guide to the management of allergic reaction to antivenom
