Aging: Oxidative Stress and Dietary Antioxidants

by PhD Preedy BSc (Editor), FHEA Patel PhD (Editor)

Overview

Aging: Oxidative Stress and Dietary Antioxidants, Second Edition, bridges the trans-disciplinary divide and covers the science of oxidative stress in aging and the therapeutic use of natural antioxidants in the food matrix in a single volume. The second edition covers new trials and investigations used to determine the comprehensive properties of antioxidants, food items and extracts, as well as any adverse properties they may have. It has been updated to include new clinical human trials and a new section dedicated to animal models of aging. Throughtout the book the processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this. Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging. This will aid in better research, treatment and outcome for patients. - Compares information related to mitochondrial oxidative stress in one disease to diet-related strategies in other unrelated diseases - Provides an understanding of cell signalling leading to new suggestions of preventative or therapeutic strategies - Includes a new section dedicated to animal models of aging

Product Details

ISBN-13:	9780128188118
Publisher:	Elsevier Science & Technology Books
Publication date:	05/24/2020
Sold by:	Barnes & Noble
Format:	eBook
Pages:	398
File size:	66 MB
Note:	This product may take a few minutes to download.

About the Author

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Vinood B. Patel, BSc, PhD, FRSC, is currently Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of liver disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress in neurological disorders and iron dysregulation in diabetes. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to the use or investigation of active agents or components. These books include The Handbook of Nutrition, Diet, and Epigenetics, Branched Chain Amino Acids in Clinical Nutrition, Cancer: Oxidative Stress and Dietary Antioxidants, Toxicology: Oxidative Stress and Dietary Antioxidants, Molecular Nutrition: Vitamins, The Neuroscience of Pain, Cognitive Behavioural Therapy. He is Editor of the ten-volume series Biomarkers in Disease: Methods, Discoveries and Applications.

Table of Contents

Preface I. Oxidative stress and aging 1. Oxidative stress and mir-200cAlessandra Magenta, Maria Cristina Florio, Marco D'Agostino, Sara Sileno 2. Caloric restriction, reactive oxygen species, and longevityMiyuki Kobara, Hiroe Toba, Tetsuo Nakata 3. Cardiovascular disease in aging and the role of oxidative stressLucie Orliaguet, Vinood B. Patel, Victor R. Preedy, Fawaz Alzaid 4. Aging, oxidative stress, mitochondrial dysfunction, and the liverJanice G. Lozada-Delgado, Carlos A. Torres-Ramos, Sylvette Ayala-Peña 5. Culprit effect of oxidative stress in the development of parkinson's disease: a conundrum of senescenceRahul Saxena, Gladys Rai 6. Linking bone cells, aging, and oxidative stress: osteoblasts, osteoclasts, osteocytes, and bone marrow cellsJuan A. Ardura, Luis Álvarez-Carrión, Arancha R. Gortázar, Verónica Alonso 7. Oxidative stress, senescence and mediterranean diet effects on osteoarthritisSergio Ammendola, Anna Scotto D'Abusco 8. Arthritis as a disease of aging and changes in antioxidant statusRahul Saxena, Jyoti Batra 9. Oxidative stress and sarcopeniaFrancesco Bellanti, Aurelio Lo Buglio, Gianluigi Vendemiale 10. Oxidative stress and hypertension in old age: the role of physical exerciseClodoaldo Antônio De Sá, Vanessa Corralo, Francielle Garghetti Battiston, Maria Isabel Gonc¸ Alves Da Silva 11. Linking senescence, apoptosis, and oxidative stress in fertilityMathias Abiodun Emokpae, Osaretin Godwin Igharo 12. Antioxidant capacity and menopausal symptomsGity Sotoudeh, Maryam Abshirini II. Antioxidants and aging 13. Reference dietary requirements of antioxidant vitamins in the older adultsMina Yamazaki Price, Victor R. Preedy 14. Oxidative stress and antioxidants in elderly womenBrunna Cristina Bremer Boaventura, Patricia Faria Di Pietro, Francieli Cembranel 15. Caffeine and its analogs, antioxidants, and applicationsBeata Jasiewicz, Arleta Sierakowska 16. Coenzyme q10 as an antioxidant in the elderlyElena M. Yubero-Serrano, Francisco M. Gutierrez-Mariscal, Antonio Garcia-Rios, Javier Delgado-Lista, Pablo Pérez-Martinez, Antonio Camargo, Francisco Perez-Jimenez, Jose Lopez-Miranda 17. The role of coenzyme q10 in the protection of bone health during agingJosé L. Quiles, José M. Romero-Márquez, Mariá D. Navarro-Hortal, Maurizio Battino, Alfonso Varela-López 18. Coenzyme q10 supplementation in agingGuillermo López-Lluch, Plácido Navas 19. Crocus sativus l. (saffron) extract antioxidant potential and use in agingSaeed Samarghandian, Tahereh Farkhondeh, Tayebeh Zeinali 20. Pharmacological profile of γ-oryzanol: its antioxidant mechanisms and its effects in age-related diseasesWiramon Rungratanawanich, Giulia Abate, Daniela Uberti 21. Herbs including shell ginger, antioxidant profiles, aging, and longevity in okinawa, japan: a critical analysis of current conceptsRolf Teschke, Tran Dang Xuan 22. Lycopene as an antioxidant in the prevention and treatment of postmenopausal osteoporosisL.G. Rao, E.S. Mackinnon, A.V. Rao 23. Medicinal plants, antioxidant potential, and applications to agingWaseem Hassan, Mehreen Zafar, Jean Paul Kamdem 24. Antioxidant and anti-inflammatory role of melatonin in alzheimer's neurodegenerationSergio A. Rosales-Corral, Russel J. Reiter, Xiaoyan Liu 25. Murici (byrsonima crassifolia (l.) Kunth): antioxidant effects and application to agingMariana Séfora Bezerra Sousa Diego De Souza Buarque 26. Natural products in aging skinMahendran Sekar 27. Antioxidant properties and applications of ophiopogon japonicus root for age-related diseaseYumi Kitahiro, Makio Shibano 28. Passion fruit seed: its antioxidative extracts and potency in protection of skin agingNattaya Lourith, Mayuree Kanlayavattanakul 29. Phaseolus vulgaris l. As a functional food for aging protectionEunice Santos, Guilhermina Marques, Teresa Lino-Neto 30. Quercetin and resveratrol, aging and kidneyMina Hemmati, Maryam Moossavi 31. Rambutan fruits extract in aging skinMahendran Sekar 32.

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From the Publisher

Translational coverage of how dietary antioxidants and oxidative stress both contribute to and protect against premature aging and the aging process