Sequence Kernel for Z’ Factor
By Karol Kozak
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By Karol Kozak
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RNA interference (RNAi) high-content screening (HCS) enables massive parallel gene
silencing and is increasingly being used to reveal novel connections between genes and disease-relevant phenotypes. The application of genome-scale RNAi relies on the
development of high quality HCS assays. The Z’ factor statistic provides a way to evaluate whether or not screening run conditions (reagents, protocols, instrumentation, kinetics, and other conditions not directly related to the test compounds) ar...
silencing and is increasingly being used to reveal novel connections between genes and disease-relevant phenotypes. The application of genome-scale RNAi relies on the
development of high quality HCS assays. The Z’ factor statistic provides a way to evaluate whether or not screening run conditions (reagents, protocols, instrumentation, kinetics, and other conditions not directly related to the test compounds) ar...























