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Bioconjugate Techniques / Edition 3
     

Bioconjugate Techniques / Edition 3

by Greg T. Hermanson
 

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ISBN-10: 0123822394

ISBN-13: 9780123822390

Pub. Date: 09/02/2013

Publisher: Elsevier Science

Bioconjugate Techniques,3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with

Overview

Bioconjugate Techniques,3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

  • Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab
  • Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates
  • Features full color illustrations
  • Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

Product Details

ISBN-13:
9780123822390
Publisher:
Elsevier Science
Publication date:
09/02/2013
Edition description:
New Edition
Pages:
1200
Sales rank:
1,221,234
Product dimensions:
8.80(w) x 11.00(h) x 2.30(d)

Table of Contents

1. Introduction to Bioconjugation

2. Functional Targets for Bioconjugation

3. The Reactions of Bioconjugation

4. Zero-Length Crosslinkers

5. Homobifunctional Crosslinkers

6. Heterobifunctional Crosslinkers

7. Trifunctional Crosslinkers

8. Dendrimers and Dendrons

9. Cross-Bridges and Cleavable Reagent Systems

10. Fluorescent Probes

11. (Strept)avidin - Biotin Systems

12. Isotopic Labeling Techniques

13. Silane Coupling Agents

14. Microparticles and Nanoparticles

15. Immobilization of Ligands on Chromatography Supports

16. Buckyballs, Fullerenes, and Carbon Nanotubes

17. Chemoselective Ligation; Bioorthogonal Reagents

18. PEGylation & Synthetic Polymer Modification

19. Vaccine and Immunogen Conjugates

20. Antibody Modification and Conjugation

21. Liposome Conjugates and Derivatives

22. Enzyme Modification and Conjugation

23. Nucleic Acid and Oligonucleotide Modification and Conjugation

24. Bioconjugation for the Study of Protein Interactions

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