Acute Coronary Syndromes

by David A. Morrow MD, MPH (Editor), Robert P. Giugliano MD, ScM (Editor)

Overview

Part of the renowned Braunwald family of references, Acute Coronary Syndromes, Second Edition: A Companion to Braunwald’s Heart Disease provides the tools and knowledge you need for effective diagnosis, evaluation, and management of patients with acute coronary syndrome. Concise and easy to use, this fully revised volume explores the most recent tools for diagnosis and therapeutic decision-making, as well as the full range of available management strategies, providing outcomes data for each strategy. This book also includes regular updates with late-breaking clinical trials, reviews of important new articles, and the latest guidance on clinical practice, all selected and masterfully edited by Dr. Eugene Braunwald.

• Provides thorough discussions of ECG, established and emerging biochemical markers, angiography, nuclear cardiology, echocardiography, and cardiac MRI and CT
• Features an extensive treatment section that covers the latest drugs and most recent clinical trials of antithrombotic therapy, novel anti-inflammatory approaches, coronary revascularization, and approaches to reperfusion injury and ventricular remodeling
• Reflects the 2021 ACC/AHA Guidelines for the Evaluation and Diagnosis of Chest Pain, and features increased visual aids such as bulleted lists, graphs, tables, and algorithms throughout
• Discusses special considerations for the evaluation of acute coronary syndromes in the emergency department, and use of advanced technologies in cardiac critical care
• Covers key topics such as in-hospital complications, cardiogenic shock, transitions to post-discharge care, and cardiac rehabilitation
• Includes practice-oriented material that highlights management-focused, practical topics covering expert approaches for areas of uncertainty
• Offers guidance on the management of special populations
• An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

Product Details

ISBN-13:	9780443118692
Publisher:	Elsevier Health Sciences
Publication date:	12/26/2025
Series:	Companion to Braunwald's Heart Disease
Edition description:	2nd ed.
Pages:	450
Product dimensions:	8.50(w) x 10.88(h) x (d)

About the Author

Dr. David A. Morrow is the director of the Cardiac Intensive Care Unit (CICU) at Brigham and Women’s Hospital (BWH). A cardiovascular medicine specialist, he is also a professor of medicine at Harvard Medical School (HMS).

He received his medical degree from HMS. He completed an internal medicine residency and a cardiology fellowship at BWH. He is board certified in internal medicine and cardiovascular disease. Dr. Morrow’s clinical interests include cardiac intensive care and ischemic heart disease. At the CICU, he designed and implemented a new multidisciplinary program—the BWH Acute Aortic Syndrome Program and the Shock Team—that helps streamline and improve aortic care and shock management. Dr. Morrow’s research centers on clinical management strategies and novel therapeutics for ischemic heart disease. This includes both stable and unstable ischemic syndromes, with a related focus on the use of cardiovascular biomarkers for risk stratification and clinical decision-making. The author of over 200 peer-reviewed publications, he has received research funding from the National Institutes of Health. Castle Connolly has listed him as one of America’s Top Doctors.

Dr. Giugliano is a Staff Physician in the Cardiovascular Division at Brigham and Women's Hospital and Professor of Medicine at Harvard Medical School. DR Giugliano obtained his medical degree from HMS. He completed a residency and chief residency program in internal medicine from Cedars-Sinai Medical Center in Los Angeles. He then completed a cardiology fellowship at Massachusetts General Hospital and an internal medicine research fellowship with TIMI at BWH. He is board certified in cardiovascular disease. Dr Giugliano has authored over 250 peer-reviewed articles and chapters, serves as a reviewer and/or Editorial Board for over two dozen journals, and has delivered hundreds of lectures throughout the US and abroad.

Table of Contents

1. Overview of the Patient with Acute Coronary Syndrome
2. Classification of acute coronary syndromes

Initial Evaluation and Risk Stratification
3. Pre-hospital assessment and systems of care
4. Clinical approach to suspected acute coronary syndrome
5. Acute cardiac imaging for patients with chest pain in the Emergency Department
6. Risk statification in acute coronary syndromes
7. Emergency department evaluation of the lower risk patient: Who can you send home?

Initial Treatment
8. Selection of reperfusion therapy and transfer strategies for patients with STEMI
9. Fibrinolytic therapy for patients with STEMI
10. Revascularization in non-ST-segment elevation acute coronary syndrome-for whom, when, and how?
11. Approach to percutaneous coronary intervention for acute coronary syndrome
12. Selection of initial anticoagulant therapy
13. Initial antiplatelet therapy for ACS

Inhospital Evaluation
14. Approach to non-invasive testing after presentation with acute coronary syndrome
15. Echocardiography in patients with acute coronary syndrome
16. Nuclear cardiology techniques after acute coronary syndrome
17. Cardiac magnetic resonance imaging after myocardial infarction
18. Optical Coherence Tomography and Other Intracoronary Diagnostic Procedures

In hospital Complications
19. Recurrent ischemia: detection, diagnosis, and outcomes
20. Reperfusion injury: prevention and management
21. Heart failure and cardiogenic shock after ACS
22. Mechanical complications of ACS
23. Arrhythmias and sudden cardiac death after myocardial infarction
24. Epidemiology and management of bleeding in ACS
Secondary Prevention after ACS
25. Old and new oral anticoagulant therapy after ACS
26. Antiplatelet therapy after ACS
27. Anti-inflammatory therapy in ACS
28. Management of the patient with ACS in the absence of obstructive coronary artery disease (MINOCA, SCAD, vasospasm)
29. New concepts in cardiac rehabilitation and secondary prevention after ACS
30. Tackling the problem of adverse ventricular remodeling after myocardial infarction

Epidemiolgy and Pathobiology
31. The evolving epidemiology and natural history of acute coronary syndromes
32. New and emerging insights into the pathobiology of acute coronary syndromes, healing, and remodeling

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From the Publisher

State-of-the-art, comprehensive coverage of acute coronary syndromes from the Braunwald's name you trust