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Enzyme-Prodrug Strategies for Cancer Therapy

By Roger G. Melton (Editor), Richard J. Knox (Editor)
eBook
$209.00
By Roger G. Melton (Editor), Richard J. Knox (Editor)
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Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity. Antibody delivery combined with the amplification provided by the enzymatic activation of prodrugs enables selection to be made between tumour and normal tissue. ADEPT offers a novel field of opportunities in the therapy of systemic cancer and may be a major advance for the treatment of solid tumours.
This book is the first to describe ADEPT in detail. Each c...