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Genome Editing Tools and Gene Drives: A Brief Overview

By Reagan Mudziwapasi, Ringisai Chekera, Clophas Zibusiso Ncube, Irvonnie Shoko, Berlinda Ncube, Thandanani Moyo, Jeffrey Godfrey Chimbo, Jemethious Dube, Farai Faustos Mashiri, Moira Amanda Mubani, Duncan Maruta, Charity Chimbo, Mpumuzi Masuku, Ryman Shoko, Rutendo Patricia Nyamusamba, Fortune Ntengwa Jomane
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By Reagan Mudziwapasi, Ringisai Chekera, Clophas Zibusiso Ncube, Irvonnie Shoko, Berlinda Ncube, Thandanani Moyo, Jeffrey Godfrey Chimbo, Jemethious Dube, Farai Faustos Mashiri, Moira Amanda Mubani, Duncan Maruta, Charity Chimbo, Mpumuzi Masuku, Ryman Shoko, Rutendo Patricia Nyamusamba, Fortune Ntengwa Jomane
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Genome-editing methods are becoming routine tools for molecular and cell biologists. Such tools include ZFNs, CRISPR, megaTALs and TALENs. These tools are revolutionizing the creation of precisely manipulated genomes to modify the characteristics of organisms or cells. Additionally, gene drives have altered the way we understand inheritance laws. They give us the ability to have total control of the inheritance of traits of choice and importance. This succinct volume summarizes the history,...

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Medicine & NursingMedicineBasic SciencesBiomedical Technology & Engineering