Hepatocytes: Methods and Protocols

This volume details experimental prools to study structure and function of hepaytes in vivo and in vitro, and for characterizing heterogeneity and plasticity of hepaytes in healthy and in injured liver. Chapters guide readers through separating hepayte subfractions, characterizing the heterogeneity, novel culture systems, hepayte—like cells from human pluripotent stem cells, analyzing drug metabolism, monitoring protein sorting, manipulating gene expression, and methods for expanding primar...