Homology Modeling: Methods and Protocols

Knowledge about protein tertiary structure can guide experiments, assist in the understanding of structure—function relationships, and aid the design of new therapeutics for disease. Homology modeling is an in silico method that predicts the tertiary structure of an amino acid sequence based on a homologous experimentally determined structure. In, Homology Modelling: Methods and Prools experts in the field describe each homology modeling step from first principles, provide case studies for ...