Ion Channels: A Laboratory Manual

The propagation of signals through the nervous system depends on rapid changes in electric potential across cell membranes. These changes are mediated by ion channels—macromolecular pores that facilitate the passage of specific ions (e.g., K+ or Na+) through cell membranes in response to various signals. Defects in ion channels can lead to diseases such as epilepsy.

This laboratory manual provides state-of-the-art techniques for investigating ion channel properties and activity, particularly...