Marks' Basic Medical Biochemistry: A Clinical Approach

by Michael A. Lieberman, Alisa Peet

Overview

Marks’ Basic Medical Biochemistry: A Clinical Approach, 6th Edition links biochemistry to physiology and pathophysiology, empowering students to confidently apply fundamental concepts to the practice of medicine — from diagnosing patients to recommending effective treatments. This proven, application-centered approach builds biochemical coverage around related clinical concepts to anchor students’ understanding to a clinical context from day one. Intuitively organized chapters center on hypothetical patient vignettes to emphasize clinical applications, and helpful icons, images, and review questions make complex concepts easier to grasp.

Product Details

ISBN-13:	9781975150167
Publisher:	Wolters Kluwer Health
Publication date:	01/13/2022
Sold by:	Barnes & Noble
Format:	eBook
Pages:	1132
File size:	217 MB
Note:	This product may take a few minutes to download.

Table of Contents

Section One: FUEL METABOLISM

• 1: Metabolic Fuels and Dietary Components
• 2: The Fed or Absorptive State
• 3: Fasting

Section Two: CHEMICAL AND BIOLOGICAL FOUNDATIONS OF BIOCHEMISTRY

• 4: Water, Acids, Bases, and Buffers
• 5: Structures of the Major Compounds of the Body
• 6: Amino Acids in Proteins
• 7: Structure-Function Relationships in Proteins
• 8: Enzymes as Catalysts
• 9: Regulation of Enzymes
• 10: Relationship between Cell Biology and Biochemistry
• 11: Cell Signaling by Chemical Messengers

Section Three: GENE EXPRESSION AND THE SYNTHESIS OF PROTEINS

• 12: Structure of the Nucleic Acids
• 13: Synthesis of DNA
• 14: Transcription: Synthesis of RNA
• 15: Translation: Synthesis of Proteins
• 16: Regulation of Gene Expression
• 17: Use of Recombinant DNA Techniques in Medicine
• 18: The Molecular Biology of Cancer

Section Four: FUEL OXIDATION AND THE GENERATION OF ATP

• 19: Cellular Bioenergetics: ATP and O₂
• 20: Tricarboxylic Acid Cycle
• 21: Oxidative Phosphorylation and Mitochondrial Function
• 22: Generation of ATP from Glucose: Glycosis
• 23: Oxidation of Fatty Acids and Ketone Bodies
• 24: Oxygen Toxicity and Free Radical Injury
• 25: Metabolism of Ethanol

Section Five: CARBOHYDRATE METABOLISM

• 26: Basic Concepts in the Regulation of Fuel Metabolism by Insulin, Glucagon, and Other Hormones
• 27: Digestion, Absorption, and Transport of Carbohydrates
• 28: Formation and Degradation of Glycogen
• 29: Pathways of Sugar Metabolism: Pentose Phosphate Pathway, Fructose, and Galactose Metabolism
• 30: Synthesis of Glycosides, Lactose, Glycoproteins, and Glycolipids
• 31: Gluconeogenesis and Maintenance of Blood Glucose Levels

Section Six: LIPID METABOLISM

• 32: Digestion and Transport of Dietary Lipids
• 33: Synthesis of Fatty Acids, Triacylglycerols, and the Major Membrane Lipids
• 34: Cholesterol Absorption, Synthesis, Metabolism, and Fate
• 35: Metabolism of the Eicosanoids
• 36: Integration of Carbohydrate and Lipid Metabolism

Section Seven: NITROGEN METABOLISM

• 37: Protein Digestion and Amino Acid Absorption
• 38: Fate of Amino Acid Nitrogen: Urea Cycle
• L39: Synthesis and Degradation of Amino Acids
• 40: Tetrahydrofolate, Vitamin B₁₂, and S-Adenosylmethionine
• 41: Purine and Pyrimidine Metabolism
• 42: Intertissue Relationships in the Metabolism of Amino Acids

Section Eight: TISSUE METABOLISM

• 43: Actions of Hormones Regulating Fuel Metabolism
• 44: The Biochemistry of the Erythrocyte and Other Blood Cells
• 45: Blood Plasma Proteins, Coagulation and Fibrinolysis
• 46: Liver Metabolism
• 47: Metabolism of Muscle at Rest and During Exercise
• 48: Metabolism of the Nervous System
• 49: The Extracellular Matrix and Connective Tissue

Appendix: Answers to Review Questions

Index