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Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine

By Fabrice Lejeune, Hana Benhabiles, Jieshuang Jia
eBook
$100.00
By Fabrice Lejeune, Hana Benhabiles, Jieshuang Jia
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Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD).

It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. ...

Categories

Science & TechnologyBiology & Life SciencesBiologyBiology - General & MiscellaneousBiology - Molecular Biology