Periostin

This book provides a comprehensive and up-to-date review of current understanding of periostin and its importance for human health and disease. Periostin is a secretory matricellular protein that has been revealed to play key roles in fibrillogenesis and cell migration, including metastasis of cancer cells. The production of periostin is upregulated during fibrotic responses and the mechanisms by which it promotes fibrosis have become a focus of interest owing to the potential clinical bene...