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Targeted Protein Degradation: Methods and Protocols

By Angela M. Cacace (Editor), Christopher M. Hickey (Editor), Miklós Békés (Editor)
Hardcover
$249.99
By Angela M. Cacace (Editor), Christopher M. Hickey (Editor), Miklós Békés (Editor)
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This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis—targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase—induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes...

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Science & TechnologyChemistryOrganic Chemistry